Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BLM | P54132 | 1/20 | 0.52 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | PTPN1 | P18031 | 3/20 | 0.39 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.36 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.36 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.36 |
| ▸ | HDAC7 | Q8WUI4 | 2/20 | 0.36 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.36 |
| ▸ | HDAC10 | Q969S8 | 2/20 | 0.36 |
| ▸ | HDAC11 | Q96DB2 | 2/20 | 0.36 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.36 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.36 |
| ▸ | HDAC9 | Q9UKV0 | 2/20 | 0.36 |
| ▸ | HDAC5 | Q9UQL6 | 2/20 | 0.36 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.33 |
| ▸ | CDC25B | P30305 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10290507 | 0.98 | BLM (0.48) | BLMLMNAMEN1CYP3A4ALOX15 | |
| SCHEMBL6947295 | 0.84 | BLM (0.52) | BLMLMNAMEN1CYP3A4ALOX15 | |
| SCHEMBL12352432 | 0.82 | ACE2 (0.41) | MEN1KMT2AHDAC3HDAC4HDAC1 | |
| SCHEMBL22294197 | 0.82 | ACE2 (0.41) | MEN1KMT2AHDAC3HDAC4HDAC1 | |
| SCHEMBL10630172 | 0.81 | BLM (0.48) | BLMLMNAMEN1CYP3A4ALOX15 | |
| SCHEMBL10266718 | 0.80 | BLM (0.47) | BLMLMNAMEN1CYP3A4ALOX15 | |
| SCHEMBL12377272 | 0.80 | BLM (0.47) | BLMLMNAMEN1CYP3A4ALOX15 | |
| SCHEMBL10291262 | 0.80 | BLM (0.38) | BLMLMNAMAPTKDM4CKDM4A | |
| SCHEMBL12299087 | 0.78 | LMNA (0.48) | BLMLMNAMEN1CYP3A4KMT2A | |
| SCHEMBL10602150 | 0.78 | BLM (0.50) | BLMLMNAMEN1CYP3A4ALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6417009-B1 | COUPLING LIPID | AUSTRALIAN MEMBRANE AND BIOTECHNOLOGY INSTITUTE (AU) | 2002-07-09 | — | — | US | disclosed |
| EP-0912546-A1 | IMPROVED RESERVOIR COMPONENTS | AUSTRALIAN MEMBRANE AND BIOTECHNOLOGY RESEARCH INSTITUTE (AU) | 1999-05-06 | — | — | EP | disclosed |
| WO-1997043274-A1 | IMPROVED RESERVOIR COMPONENTS | AUSTRALIAN MEMBRANE AND BIOTECHNOLOGY RESEARCH INSTITUTE (AU) | 1997-11-20 | — | — | WO | disclosed |