Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RARB | P10826 | 1/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.45 |
| ▸ | MAPT | P10636 | 3/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.43 |
| ▸ | RAB9A | P51151 | 5/20 | 0.43 |
| ▸ | HPGD | P15428 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | USP2 | O75604 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 2/20 | 0.42 |
| ▸ | CNR2 | P34972 | 4/20 | 0.39 |
| ▸ | CNR1 | P21554 | 3/20 | 0.39 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.39 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.39 |
| ▸ | RELA | Q04206 | 1/20 | 0.39 |
| ▸ | THRA | P10827 | 1/20 | 0.39 |
| ▸ | THRB | P10828 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9151411 | 1.00 | RARB (0.54) | RARBSMN1; SMN2MAPTKMT2ARAB9A | |
| SCHEMBL8627223 | 0.96 | RARB (0.52) | RARBSMN1; SMN2MAPTKMT2ARAB9A | |
| SCHEMBL8628038 | 0.96 | RARB (0.52) | RARBSMN1; SMN2MAPTKMT2ARAB9A | |
| SCHEMBL8628335 | 0.96 | RARB (0.52) | RARBSMN1; SMN2MAPTKMT2ARAB9A | |
| SCHEMBL8853839 | 0.96 | RARB (0.54) | RARBSMN1; SMN2MAPTKMT2ARAB9A | |
| SCHEMBL8853514 | 0.96 | RARB (0.54) | RARBSMN1; SMN2MAPTKMT2ARAB9A | |
| SCHEMBL8853845 | 0.96 | RARB (0.54) | RARBSMN1; SMN2MAPTKMT2ARAB9A | |
| SCHEMBL8853529 | 0.96 | RARB (0.54) | RARBSMN1; SMN2MAPTKMT2ARAB9A | |
| SCHEMBL8625744 | 0.95 | RARB (0.51) | RARBSMN1; SMN2MAPTKMT2ARAB9A | |
| SCHEMBL8447769 | 0.95 | RARB (0.51) | RARBSMN1; SMN2MAPTKMT2ARAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0639189-B1 | PYRIDYLPYRIMIDINES, A METHOD OF PREPARING THEM, AND THEIR USE IN LIQUID-CRYSTAL MIXTURES | AVENTIS RES & TECH GMBH & CO (DE) | 2003-02-19 | — | — | EP | disclosed |
| EP-0541081-B1 | Compounds with only a side chain for use in liquid crystal mixtures | AVENTIS RES & TECH GMBH & CO (DE) | 2002-04-10 | — | — | EP | disclosed |
| EP-0618914-B1 | OXIRANYL METHYL ETHERS EXHIBITING CHIRALITY, AND THEIR USE AS DOPANTS IN LIQUID-CRYSTAL MIXTURES | AVENTIS RES & TECH GMBH & CO (DE) | 2001-10-17 | — | — | EP | disclosed |
| EP-0532916-B1 | 2-Fluoropyrazines, process for their preparation, and their use in liquid crystalline mixtures | HOECHST AG (DE) | 1997-11-05 | — | — | EP | disclosed |
| US-5407599-A | Cyclopropylaklyl or -alkenyl or heterocyclic compounds, process for their preparation and their use in liquid-crystalline mixtures | HOECHST AKTIENGESELLSCHAFT (DE) | 1995-04-18 | — | — | US | disclosed |
| EP-0318423-B1 | Liquid crystalline cyclopropyl alkyl or alkenylhetero rings, process for their preparation and their use in liquid-crystal mixtures | HOECHST AG (DE) | 1995-02-01 | — | — | EP | disclosed |
| EP-0532916-A1 | 2-Fluoropyrazines, process for their preparation, and their use in liquid crystalline mixtures | HOECHST AKTIENGESELLSCHAFT (DE) | 1993-03-24 | — | — | EP | disclosed |
| EP-0318423-A2 | Liquid crystalline cyclopropyl alkyl or alkenylhetero rings, process for their preparation and their use in liquid-crystal mixtures | HOECHST AKTIENGESELLSCHAFT (DE) | 1989-05-31 | — | — | EP | disclosed |