Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TNF | P01375 | 1/20 | 0.52 |
| ▸ | HDAC1 | Q13547 | 5/20 | 0.45 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.44 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.44 |
| ▸ | PPARG | P37231 | 5/20 | 0.44 |
| ▸ | PPARA | Q07869 | 5/20 | 0.44 |
| ▸ | PPARD | Q03181 | 4/20 | 0.44 |
| ▸ | HDAC6 | Q9UBN7 | 4/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.43 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.43 |
| ▸ | HDAC8 | Q9BY41 | 3/20 | 0.42 |
| ▸ | HDAC11 | Q96DB2 | 2/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | MELK | Q14680 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6945353 | 0.91 | TNF (0.51) | TNFHDAC1ADORA3ADORA2BHDAC6 | |
| SCHEMBL6952964 | 0.87 | TNF (0.53) | TNFHDAC1ADORA3ADORA2BPPARG | |
| SCHEMBL7530431 | 0.85 | PPARG (0.51) | PPARGPPARAPPARD | |
| SCHEMBL6754497 | 0.78 | PPARG (0.47) | HDAC1PPARGPPARAPPARDHDAC6 | |
| SCHEMBL7533389 | 0.78 | PPARG (0.62) | PPARGPPARAPPARDHDAC6HDAC2 | |
| SCHEMBL6956426 | 0.76 | PPARG (0.59) | TNFPPARGPPARAPPARD | |
| SCHEMBL6752369 | 0.75 | PPARG (0.46) | PPARGPPARAPPARD | |
| SCHEMBL7852911 | 0.75 | PPARA (0.72) | PPARGPPARAPPARD | |
| SCHEMBL7532542 | 0.75 | PPARA (0.72) | PPARGPPARAPPARD | |
| SCHEMBL7535616 | 0.74 | PPARA (0.66) | PPARGPPARAPPARD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0903343-B1 | Alpha-Substituted phenylpropionic acid derivative and medicine containing the same | SSP CO LTD (JP) | 2003-05-28 | — | — | EP | disclosed |
| EP-0903343-A1 | Alpha-Substituted phenylpropionic acid derivative and medicine containing the same | SSP Co., Ltd. (JP) | 1999-03-24 | — | — | EP | disclosed |