Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN1 | P18031 | 1/20 | 0.81 |
| ▸ | NR4A2 | P43354 | 4/20 | 0.71 |
| ▸ | MAOB | P27338 | 3/20 | 0.66 |
| ▸ | ERCC5 | P28715 | 1/20 | 0.59 |
| ▸ | FEN1 | P39748 | 1/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.58 |
| ▸ | HPD | P32754 | 1/20 | 0.56 |
| ▸ | SMPD1 | P17405 | 2/20 | 0.53 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.53 |
| ▸ | MEN1 | O00255 | 2/20 | 0.53 |
| ▸ | PPARA | Q07869 | 1/20 | 0.53 |
| ▸ | MAOA | P21397 | 1/20 | 0.53 |
| ▸ | LMNA | P02545 | 1/20 | 0.52 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6951340 | 0.89 | PTPN1 (1.00) | PTPN1NR4A2MAOBERCC5FEN1 | |
| SCHEMBL6946999 | 0.88 | PTPN1 (0.73) | PTPN1NR4A2MAOBERCC5FEN1 | |
| SCHEMBL1168262 | 0.84 | NR4A2 (1.00) | NR4A2MAOBKMT2AHPDMRGPRX4 | |
| SCHEMBL6946229 | 0.81 | PTPN1 (0.84) | PTPN1NR4A2MAOBERCC5FEN1 | |
| SCHEMBL6415086 | 0.80 | MAOB (0.75) | NR4A2MAOBKMT2AHPDSMPD1 | |
| SCHEMBL4640232 | 0.80 | NR4A2 (0.76) | NR4A2MAOBKMT2AHPDMRGPRX4 | |
| SCHEMBL6949871 | 0.79 | PTPN1 (0.67) | PTPN1ERCC5FEN1LMNA | |
| SCHEMBL6951859 | 0.79 | NR4A2 (0.70) | PTPN1NR4A2MAOBKMT2AHPD | |
| SCHEMBL6951854 | 0.79 | NR4A2 (0.70) | PTPN1NR4A2MAOBKMT2AHPD | |
| SCHEMBL6131764 | 0.78 | PTPN1 (0.79) | PTPN1NR4A2MAOBKMT2ASMPD1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1082121-A4 | HIV INTEGRASE INHIBITORS | MERCK & CO INC (US) | 2003-02-05 | — | — | EP | claimed |
| EP-1082121-A1 | HIV INTEGRASE INHIBITORS | Merck & Co., Inc. (US) | 2001-03-14 | — | — | EP | claimed |
| WO-1999062520-A1 | HIV INTEGRASE INHIBITORS | MERCK & CO., INC. (US) | 1999-12-09 | — | — | WO | claimed |
| EP-1082121-A4 | HIV INTEGRASE INHIBITORS | MERCK & CO INC (US) | 2003-02-05 | — | — | EP | disclosed |
| EP-1082121-A1 | HIV INTEGRASE INHIBITORS | Merck & Co., Inc. (US) | 2001-03-14 | — | — | EP | disclosed |
| WO-1999062520-A1 | HIV INTEGRASE INHIBITORS | MERCK & CO., INC. (US) | 1999-12-09 | — | — | WO | disclosed |