Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 10/20 | 0.45 |
| ▸ | MEN1 | O00255 | 8/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 8/20 | 0.45 |
| ▸ | TP53 | P04637 | 1/20 | 0.45 |
| ▸ | GLA | P06280 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | NPC1 | O15118 | 6/20 | 0.42 |
| ▸ | RAB9A | P51151 | 6/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.42 |
| ▸ | GAA | P10253 | 3/20 | 0.42 |
| ▸ | GFER | P55789 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.40 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.40 |
| ▸ | RELA | Q04206 | 1/20 | 0.40 |
| ▸ | NSD2 | O96028 | 1/20 | 0.40 |
| ▸ | ALPL | P05186 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL396167 | 0.67 | — | — | |
| SCHEMBL15485795 | 0.66 | MAPT (0.46) | MAPTMEN1KMT2ATP53GLA | |
| SCHEMBL925818 | 0.64 | MAPT (0.47) | MAPTMEN1KMT2ATP53GLA | |
| SCHEMBL8339941 | 0.64 | — | — | |
| SCHEMBL9742712 | 0.63 | MAPT (0.72) | MAPTMEN1KMT2ATP53GLA | |
| SCHEMBL9742689 | 0.62 | MAPT (1.00) | MAPTMEN1KMT2ATP53GLA | |
| SCHEMBL3458525 | 0.62 | NPC1 (0.51) | MAPTMEN1KMT2ATP53GLA | |
| SCHEMBL7181038 | 0.60 | MAPT (0.49) | MAPTMEN1KMT2ATP53GLA | |
| SCHEMBL1365426 | 0.60 | MAPT (0.47) | MAPTMEN1KMT2ATP53GLA | |
| SCHEMBL13248348 | 0.60 | MAPT (0.49) | MAPTMEN1KMT2ATP53GLA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040171652-A1 | Antiviral and spermicidal contraceptives; 2-thiourea pyridinyl derivative containing compositions | PARKER HUGHES INSTITUTE | 2004-09-02 | — | — | US | disclosed |
| US-6774139-B1 | CONTRACEPTIVES | PARKER HUGHES INSTITUTE | 2004-08-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040171652-A1 | Antiviral and spermicidal contraceptives; 2-thiourea pyridinyl derivative containing compositions | ZP1, NASP, SAMHD1 | MAPT 4039/4885MEN1 3876/4885KMT2A 1632/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.