Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.54 |
| ▸ | TSHR | P16473 | 1/20 | 0.54 |
| ▸ | PRMT6 | Q96LA8 | 1/20 | 0.51 |
| ▸ | GAA | P10253 | 1/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.51 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.51 |
| ▸ | F2 | P00734 | 2/20 | 0.49 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.49 |
| ▸ | SPIN1 | Q9Y657 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6225676 | 0.88 | F2 (0.58) | MEN1KMT2AALDH1A1TSHRGAA | |
| SCHEMBL22954064 | 0.88 | KDM4E (0.62) | MEN1KMT2AALDH1A1TSHRPRMT6 | |
| SCHEMBL14614784 | 0.86 | MEN1 (0.55) | MEN1KMT2AALDH1A1TSHRGAA | |
| Benzylamine SCHEMBL28104706 | 0.82 | KDM4E (0.64) | MEN1KMT2AALDH1A1TSHRGAA | |
| SCHEMBL2205074 | 0.81 | TSHR (0.59) | MEN1KMT2AALDH1A1TSHRGAA | |
| SCHEMBL6226913 | 0.81 | MEN1 (0.50) | MEN1KMT2AALDH1A1TSHRGAA | |
| SCHEMBL3179790 | 0.80 | TSHR (0.59) | MEN1KMT2AALDH1A1TSHRGAA | |
| SCHEMBL24732909 | 0.80 | PRMT6 (0.56) | MEN1KMT2AALDH1A1TSHRPRMT6 | |
| SCHEMBL9831262 | 0.80 | KDM4E (0.64) | MEN1KMT2AALDH1A1TSHRGAA | |
| SCHEMBL2760407 | 0.80 | MEN1 (0.62) | MEN1KMT2AALDH1A1TSHRKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1019047-B1 | ANTITHROMBOTIC AGENTS | LILLY CO ELI (US) | 2003-11-05 | — | — | EP | disclosed |
| US-6541499-B1 | Antithrombotic agents | ELI LILLY AND COMPANY | 2003-04-01 | — | — | US | disclosed |
| EP-1019047-A4 | ANTITHROMBOTIC AGENTS | LILLY CO ELI (US) | 2001-06-13 | — | — | EP | disclosed |
| EP-1019047-A1 | ANTITHROMBOTIC AGENTS | ELI LILLY AND COMPANY (US) | 2000-07-19 | — | — | EP | disclosed |
| WO-1998048800-A1 | ANTITHROMBOTIC AGENTS | ELI LILLY AND COMPANY (US) | 1998-11-05 | — | — | WO | disclosed |