Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.54 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.54 |
| ▸ | HTT | P42858 | 3/20 | 0.53 |
| ▸ | PSMD14 | O00487 | 1/20 | 0.50 |
| ▸ | GAA | P10253 | 1/20 | 0.50 |
| ▸ | MMP9 | P14780 | 1/20 | 0.47 |
| ▸ | MAOA | P21397 | 1/20 | 0.47 |
| ▸ | MAOB | P27338 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 3/20 | 0.45 |
| ▸ | MEN1 | O00255 | 3/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.45 |
| ▸ | LMNA | P02545 | 2/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.45 |
| ▸ | TP53 | P04637 | 2/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.45 |
| ▸ | PRNP | P04156 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6946445 | 0.83 | TSHR (0.62) | TSHRMAPK1HTTGAAKDM4E | |
| SCHEMBL6953023 | 0.81 | CYP1A2 (0.53) | TSHRHTTPSMD14GAAKDM4E | |
| SCHEMBL221728 | 0.81 | TSHR (0.60) | TSHRMAPK1HTTGAAMMP9 | |
| SCHEMBL6946463 | 0.77 | KDM4E (0.45) | TSHRMAPK1HTTPSMD14GAA | |
| SCHEMBL17380973 | 0.73 | POLB (0.58) | TSHRHTTKDM4EHSD17B10RAB9A | |
| SCHEMBL15643536 | 0.73 | MAPT (0.65) | HTTKDM4EHSD17B10NPC1MAPT | |
| SCHEMBL945578 | 0.71 | POLB (0.61) | HTTMAPTMEN1KMT2ALMNA | |
| SCHEMBL10615359 | 0.71 | KDM4E (0.60) | TSHRHTTMMP9MAOAMAOB | |
| SCHEMBL7018296 | 0.70 | RAB9A (0.58) | TSHRHTTPSMD14GAAKDM4E | |
| SCHEMBL14499768 | 0.70 | GAA (0.57) | TSHRHTTPSMD14GAAKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0936218-B1 | BENZIMIDAZOLE DERIVATIVES | MOCHIDA PHARM CO LTD (JP) | 2003-04-02 | — | — | EP | disclosed |
| US-6387938-B1 | Benzimidazole derivatives | MOCHIDA PHARMACEUTICAL CO., LTD. (JP) | 2002-05-14 | — | — | US | disclosed |
| EP-0936218-A1 | NOVEL BENZIMIDAZOLE DERIVATIVES | MOCHIDA PHARMACEUTICAL CO., LTD. (JP) | 1999-08-18 | — | — | EP | disclosed |