Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RARB | P10826 | 4/20 | 0.65 |
| ▸ | RAB9A | P51151 | 7/20 | 0.65 |
| ▸ | NPC1 | O15118 | 5/20 | 0.65 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.65 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.65 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.65 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.61 |
| ▸ | MAPT | P10636 | 4/20 | 0.61 |
| ▸ | HPGD | P15428 | 3/20 | 0.61 |
| ▸ | MEN1 | O00255 | 2/20 | 0.61 |
| ▸ | USP2 | O75604 | 2/20 | 0.61 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.61 |
| ▸ | GAA | P10253 | 1/20 | 0.61 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.57 |
| ▸ | CASP3 | P42574 | 1/20 | 0.54 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.54 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.54 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.54 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.51 |
| ▸ | LMNA | P02545 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14295767 | 1.00 | RARB (0.65) | RARBRAB9ANPC1SMN1; SMN2KDM4E | |
| SCHEMBL9268500 | 1.00 | RARB (0.65) | RARBRAB9ANPC1SMN1; SMN2KDM4E | |
| SCHEMBL13029249 | 0.98 | RARB (0.63) | RARBRAB9ANPC1SMN1; SMN2KDM4E | |
| SCHEMBL2774683 | 0.98 | RARB (0.63) | RARBRAB9ANPC1SMN1; SMN2KDM4E | |
| SCHEMBL9636338 | 0.98 | RARB (0.63) | RARBRAB9ANPC1SMN1; SMN2KDM4E | |
| SCHEMBL10342131 | 0.98 | RARB (0.63) | RARBRAB9ANPC1SMN1; SMN2KDM4E | |
| SCHEMBL7910730 | 0.98 | RARB (0.63) | RARBRAB9ANPC1SMN1; SMN2KDM4E | |
| SCHEMBL9436035 | 0.98 | RARB (0.63) | RARBRAB9ANPC1SMN1; SMN2KDM4E | |
| SCHEMBL7121080 | 0.98 | RARB (0.63) | RARBRAB9ANPC1SMN1; SMN2KDM4E | |
| SCHEMBL9241350 | 0.98 | RARB (0.63) | RARBRAB9ANPC1SMN1; SMN2KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0639189-B1 | PYRIDYLPYRIMIDINES, A METHOD OF PREPARING THEM, AND THEIR USE IN LIQUID-CRYSTAL MIXTURES | AVENTIS RES & TECH GMBH & CO (DE) | 2003-02-19 | — | — | EP | disclosed |
| EP-0532916-B1 | 2-Fluoropyrazines, process for their preparation, and their use in liquid crystalline mixtures | HOECHST AG (DE) | 1997-11-05 | — | — | EP | disclosed |
| US-5562859-A | SWITCHING AND DISPLAY DEVICE | HOECHST AKTIENGESELLSCHAFT (DE) | 1996-10-08 | — | — | US | disclosed |
| US-5443754-A | Pyridylpyrimidines, a process for their preparation and their use in liquid-crystalline mixtures | HOECHST AKTIENGESELLSCHAFT (DE) | 1995-08-22 | — | — | US | disclosed |
| EP-0532916-A1 | 2-Fluoropyrazines, process for their preparation, and their use in liquid crystalline mixtures | HOECHST AKTIENGESELLSCHAFT (DE) | 1993-03-24 | — | — | EP | disclosed |