Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 8/20 | 0.98 |
| ▸ | NPC1 | O15118 | 7/20 | 0.98 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.98 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.98 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.98 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.98 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.98 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.62 |
| ▸ | MAPT | P10636 | 5/20 | 0.62 |
| ▸ | LMNA | P02545 | 3/20 | 0.62 |
| ▸ | WDR5 | P61964 | 2/20 | 0.62 |
| ▸ | ENGASE | Q8NFI3 | 2/20 | 0.62 |
| ▸ | CYP2C8 | P10632 | 2/20 | 0.62 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.62 |
| ▸ | TSHR | P16473 | 2/20 | 0.62 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.62 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.62 |
| ▸ | HPGD | P15428 | 2/20 | 0.62 |
| ▸ | SARM1 | Q6SZW1 | 1/20 | 0.62 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.62 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Lansoprazole Sulfide SCHEMBL30053816 | 0.99 | RAB9A (1.00) | RAB9ANPC1CYP1A2CYP2D6CYP2C9 | |
| Lansoprazole Sulfide SCHEMBL106519 | 0.99 | RAB9A (1.00) | RAB9ANPC1CYP1A2CYP2D6CYP2C9 | |
| Lansoprazole Sulfide SCHEMBL1680900 | 0.98 | RAB9A (0.98) | RAB9ANPC1CYP1A2CYP2D6CYP2C9 | |
| Lansoprazole Sulfide SCHEMBL1681186 | 0.98 | RAB9A (0.98) | RAB9ANPC1CYP1A2CYP2D6CYP2C9 | |
| Lansoprazole Sulfide SCHEMBL1681462 | 0.94 | RAB9A (0.90) | RAB9ANPC1CYP1A2CYP2D6CYP2C9 | |
| Lansoprazole Sulfide SCHEMBL8184520 | 0.93 | RAB9A (0.89) | RAB9ANPC1CYP1A2CYP2D6CYP2C9 | |
| SCHEMBL29323856 | 0.92 | RAB9A (0.86) | RAB9ANPC1CYP1A2CYP2D6CYP2C9 | |
| SCHEMBL6440543 | 0.91 | RAB9A (0.85) | RAB9ANPC1CYP1A2CYP2D6CYP2C9 | |
| Water SCHEMBL6737292 | 0.90 | RAB9A (0.83) | RAB9ANPC1CYP1A2CYP2D6CYP2C9 | |
| Water SCHEMBL6737289 | 0.90 | RAB9A (0.83) | RAB9ANPC1CYP1A2CYP2D6CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0944617-B1 | CRYSTALS OF BENZIMIDAZOLE DERIVATIVES AND THEIR PRODUCTION | TAKEDA CHEMICAL INDUSTRIES LTD (JP) | 2003-05-14 | — | — | EP | disclosed |
| US-6002011-A | Crystals of benzimidazole derivatives and their production | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1999-12-14 | — | — | US | disclosed |
| EP-0944617-A1 | CRYSTALS OF BENZIMIDAZOLE DERIVATIVES AND THEIR PRODUCTION | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1999-09-29 | — | — | EP | disclosed |
| WO-1998021201-A1 | CRYSTALS OF BENZIMIDAZOLE DERIVATIVES AND THEIR PRODUCTION | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1998-05-22 | — | — | WO | disclosed |