Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.52 |
| ▸ | MEN1 | O00255 | 2/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | SELP | P16109 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | ATM | Q13315 | 1/20 | 0.31 |
| ▸ | PDCD1 | Q15116 | 1/20 | 0.30 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17550996 | 0.91 | L3MBTL1 (0.53) | L3MBTL1KMT2AMEN1ALDH1A1ADRA1A | |
| SCHEMBL17550989 | 0.91 | L3MBTL1 (0.53) | L3MBTL1KMT2AMEN1ALDH1A1ADRA1A | |
| SCHEMBL17550987 | 0.91 | L3MBTL1 (0.53) | L3MBTL1KMT2AMEN1ALDH1A1ADRA1A | |
| SCHEMBL13205072 | 0.91 | L3MBTL1 (0.57) | L3MBTL1KMT2AMEN1ALDH1A1ADRA1A | |
| SCHEMBL14449231 | 0.91 | L3MBTL1 (0.57) | L3MBTL1KMT2AMEN1ALDH1A1ADRA1A | |
| SCHEMBL6951799 | 0.90 | L3MBTL1 (0.52) | L3MBTL1KMT2AMEN1ALDH1A1ADRA1A | |
| SCHEMBL6952628 | 0.90 | L3MBTL1 (0.68) | L3MBTL1KMT2AMEN1ALDH1A1ADRA1A | |
| SCHEMBL13024785 | 0.88 | L3MBTL1 (0.52) | L3MBTL1KMT2AMEN1ALDH1A1SELP | |
| SCHEMBL10073953 | 0.86 | L3MBTL1 (0.47) | L3MBTL1KMT2AMEN1ALDH1A1ADRA1A | |
| SCHEMBL17636518 | 0.86 | L3MBTL1 (0.47) | L3MBTL1KMT2AMEN1ALDH1A1ADRA1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6534481-B1 | Antithrombin III binding domain consisting of a concatenation of five monosaccharides supporting a total of two carboxylic acid functions and at least four sulpho groups, said domain being directly bound at the non-reducing end by a thrombin | SANOFI-SYNTHELABO (FR) | 2003-03-18 | — | — | US | disclosed |
| EP-0912613-B1 | SYNTHETIC POLYSACCHARIDES, PREPARATION METHOD THEREFOR AND PHARMACEUTICAL COMPOSITIONS CONTAINING SAME | SANOFI SYNTHELABO (FR) | 2002-09-25 | — | — | EP | disclosed |