Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIA4 | P48058 | 1/20 | 0.45 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.43 |
| ▸ | ESRRG | P62508 | 3/20 | 0.42 |
| ▸ | SLC13A5 | Q86YT5 | 2/20 | 0.41 |
| ▸ | RECQL | P46063 | 1/20 | 0.41 |
| ▸ | ESRRB | O95718 | 1/20 | 0.40 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | TYR | P14679 | 1/20 | 0.39 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6940712 | 1.00 | GRIA4 (0.45) | GRIA4KCNH2TP53TSHREPHX1 | |
| SCHEMBL1660004 | 0.85 | GRIA4 (0.47) | GRIA4KCNH2TP53TSHREPHX1 | |
| SCHEMBL9848367 | 0.84 | KCNH2 (0.42) | GRIA4KCNH2TP53TSHRESRRG | |
| SCHEMBL9848370 | 0.84 | KCNH2 (0.42) | GRIA4KCNH2TP53TSHRESRRG | |
| SCHEMBL21585480 | 0.83 | ESR1 (0.52) | TSHRESRRGESRRBLMNA | |
| SCHEMBL21524662 | 0.83 | CYP1A2 (0.36) | GRIA4KCNH2TSHRESRRG | |
| Hydrochloric Acid SCHEMBL9848493 | 0.82 | KCNH2 (0.41) | GRIA4KCNH2TP53TSHRESRRG | |
| SCHEMBL5644111 | 0.79 | CYP1A2 (0.45) | KCNH2 | |
| SCHEMBL108731 | 0.79 | ESR1 (0.52) | KCNH2TSHRSIGMAR1LMNA | |
| SCHEMBL14839515 | 0.78 | ADRB2 (0.44) | GRIA4KCNH2TP53TSHRESRRG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2003103653-A1 | METHODS OF TREATING ALZHEIMER'S DISEASE USING ARYL ALKANOIC ACID AMIDES | ELAN PHARMACEUTICALS, INC. (US) | 2003-12-18 | — | — | WO | disclosed |