Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.52 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.52 |
| ▸ | MAP2K1 | Q02750 | 14/20 | 0.50 |
| ▸ | MAP2K2 | P36507 | 3/20 | 0.50 |
| ▸ | CSNK2A2 | P19784 | 2/20 | 0.50 |
| ▸ | RAF1 | P04049 | 1/20 | 0.50 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.50 |
| ▸ | CSNK2B | P67870 | 1/20 | 0.50 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.50 |
| ▸ | CSNK2A3 | Q8NEV1 | 1/20 | 0.50 |
| ▸ | AURKC | Q9UQB9 | 1/20 | 0.50 |
| ▸ | CAMK2A | Q9UQM7 | 1/20 | 0.50 |
| ▸ | SMC2 | O95347 | 1/20 | 0.36 |
| ▸ | EGFR | P00533 | 1/20 | 0.36 |
| ▸ | SMC1A | Q14683 | 1/20 | 0.36 |
| ▸ | AAK1 | Q2M2I8 | 1/20 | 0.36 |
| ▸ | Q6ZSR9 | Q6ZSR9 | 1/20 | 0.36 |
| ▸ | BMP2K | Q9NSY1 | 1/20 | 0.36 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6945701 | 0.91 | MAP2K1 (0.56) | MEN1KMT2ATDP1MAP2K1MAP2K2 | |
| SCHEMBL6945680 | 0.90 | MAP2K1 (0.57) | MEN1KMT2ATDP1MAP2K1MAP2K2 | |
| SCHEMBL6947424 | 0.89 | MEN1 (0.63) | MEN1KMT2ATDP1MAP2K1MAP2K2 | |
| SCHEMBL6946645 | 0.89 | MEN1 (0.64) | MEN1KMT2ATDP1MAP2K1MAP2K2 | |
| SCHEMBL6944499 | 0.82 | MEN1 (0.62) | MEN1KMT2ATDP1MAP2K1MAP2K2 | |
| SCHEMBL6943891 | 0.81 | MAP2K1 (0.74) | MEN1KMT2ATDP1MAP2K1MAP2K2 | |
| SCHEMBL6947374 | 0.81 | MEN1 (0.63) | MEN1KMT2ATDP1MAP2K1MAP2K2 | |
| SCHEMBL6944326 | 0.80 | MAP2K1 (0.75) | MEN1KMT2ATDP1MAP2K1MAP2K2 | |
| SCHEMBL6947451 | 0.80 | MEN1 (0.75) | MEN1KMT2ATDP1MAP2K1MAP2K2 | |
| SCHEMBL22822261 | 0.79 | MAP2K1 (0.60) | MEN1KMT2ATDP1MAP2K1MAP2K2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1202724-B1 | METHOD FOR TREATING CHRONIC PAIN USING MEK INHIBITORS | WARNER LAMBERT CO (US) | 2003-10-01 | — | — | EP | claimed |