Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2D6 | P10635 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | CASP1 | P29466 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | NR2F2 | P24468 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.37 |
| ▸ | SIGMAR1 | Q99720 | 4/20 | 0.37 |
| ▸ | EBP | Q15125 | 1/20 | 0.37 |
| ▸ | GLB1 | P16278 | 1/20 | 0.36 |
| ▸ | LTA4H | P09960 | 1/20 | 0.36 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8108441 | 0.89 | CHRNA7 (0.44) | CYP2D6KMT2ACHRNA7SIGMAR1EBP | |
| SCHEMBL6942014 | 0.89 | CHRNA7 (0.44) | CYP2D6KMT2ACHRNA7SIGMAR1EBP | |
| Methylamine SCHEMBL7228187 | 0.85 | CHRNA7 (0.41) | CYP2D6KMT2ACHRNA7SIGMAR1EBP | |
| Dimethylamine SCHEMBL6950205 | 0.84 | CHRNA7 (0.40) | CYP2D6SMN1; SMN2CHRNA7SIGMAR1EBP | |
| Dimethylamine SCHEMBL8115201 | 0.84 | CHRNA7 (0.40) | CYP2D6SMN1; SMN2CHRNA7SIGMAR1EBP | |
| Diethylamine SCHEMBL6941485 | 0.81 | CHRNA7 (0.38) | CYP2D6SMN1; SMN2CHRNA7SIGMAR1EBP | |
| SCHEMBL6941816 | 0.80 | CHRNA7 (0.37) | CYP2D6TSHRSMN1; SMN2CHRNA7 | |
| SCHEMBL6939508 | 0.80 | CHRNA7 (0.37) | CYP2D6SMN1; SMN2CHRNA7SIGMAR1GLB1 | |
| SCHEMBL8099579 | 0.80 | CHRNA7 (0.37) | CYP2D6SMN1; SMN2CHRNA7SIGMAR1GLB1 | |
| Dimethylamine SCHEMBL6941904 | 0.79 | GNAI3 (0.41) | CHRNA7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0829474-B1 | INDAZOLE DERIVATIVES HAVING MONOCYCLIC AMINO GROUP | NISSHIN SEIFUN GROUP INC (JP) | 2003-04-09 | — | — | EP | disclosed |
| US-6096746-A | Indazole compound containing a monocyclic amine structure | NISSHIN FLOUR MILLING CO., LTD. (JP) | 2000-08-01 | — | — | US | disclosed |
| US-5945434-A | TREATMENT OF GASTROINTESTINAL DISORDERS | NISSHIN FLOUR MILLING CO., LTD. (JP) | 1999-08-31 | — | — | US | disclosed |
| EP-0829474-A1 | INDAZOLE DERIVATIVES HAVING MONOCYCLIC AMINO GROUP | NISSHIN FLOUR MILLING CO., LTD. (JP) | 1998-03-18 | — | — | EP | disclosed |