Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | REN | P00797 | 15/20 | 0.36 |
| ▸ | AAK1 | Q2M2I8 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | C5 | P01031 | 1/20 | 0.35 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6044302 | 0.80 | REN (0.36) | RENABCB1 | |
| SCHEMBL13102816 | 0.77 | AAK1 (0.41) | RENAAK1 | |
| SCHEMBL8249451 | 0.77 | AAK1 (0.41) | RENAAK1 | |
| SCHEMBL14543098 | 0.74 | REN (0.41) | REN | |
| SCHEMBL9907044 | 0.74 | REN (0.44) | REN | |
| SCHEMBL14543121 | 0.74 | REN (0.39) | REN | |
| SCHEMBL13090561 | 0.74 | REN (0.44) | REN | |
| SCHEMBL6044421 | 0.73 | REN (0.33) | REN | |
| SCHEMBL6045248 | 0.71 | REN (0.53) | REN | |
| SCHEMBL841810 | 0.71 | REN (0.53) | REN |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2003103653-A1 | METHODS OF TREATING ALZHEIMER'S DISEASE USING ARYL ALKANOIC ACID AMIDES | ELAN PHARMACEUTICALS, INC. (US) | 2003-12-18 | — | — | WO | disclosed |