Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.52 |
| ▸ | SLC1A3 | P43003 | 4/20 | 0.42 |
| ▸ | SLC1A2 | P43004 | 4/20 | 0.42 |
| ▸ | SLC1A1 | P43005 | 3/20 | 0.36 |
| ▸ | LAP3 | P28838 | 6/20 | 0.35 |
| ▸ | RNPEP | Q9H4A4 | 4/20 | 0.34 |
| ▸ | ANPEP | P15144 | 4/20 | 0.34 |
| ▸ | DNPEP | Q9ULA0 | 2/20 | 0.34 |
| ▸ | LARS1 | Q9P2J5 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8585917 | 0.88 | SLC7A5 (0.53) | SLC7A5SLC1A3SLC1A2SLC1A1LAP3 | |
| SCHEMBL4889896 | 0.80 | SLC7A5 (0.57) | SLC7A5SLC1A3SLC1A2SLC1A1LAP3 | |
| SCHEMBL996374 | 0.80 | SLC7A5 (0.57) | SLC7A5SLC1A3SLC1A2SLC1A1LAP3 | |
| SCHEMBL10588085 | 0.75 | SLC7A5 (0.55) | SLC7A5SLC1A3SLC1A2SLC1A1LAP3 | |
| SCHEMBL15173245 | 0.75 | SLC7A5 (0.55) | SLC7A5SLC1A3SLC1A2SLC1A1LAP3 | |
| SCHEMBL3066899 | 0.75 | SLC7A5 (0.55) | SLC7A5SLC1A3SLC1A2SLC1A1LAP3 | |
| SCHEMBL15173244 | 0.75 | SLC7A5 (0.55) | SLC7A5SLC1A3SLC1A2SLC1A1LAP3 | |
| SCHEMBL31129064 | 0.73 | SLC7A5 (0.41) | SLC7A5SLC1A3SLC1A2SLC1A1LAP3 | |
| SCHEMBL1911122 | 0.73 | SLC7A5 (0.56) | SLC7A5SLC1A3SLC1A2SLC1A1LAP3 | |
| SCHEMBL4594704 | 0.73 | SLC7A5 (0.56) | SLC7A5SLC1A3SLC1A2SLC1A1LAP3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0956033-B1 | TOTAL SYNTHESIS OF THE AMINO HIP ANALOGUE OF DIDEMNIN A | UNIV ILLINOIS (US) | 2003-07-23 | — | — | EP | disclosed |
| US-6380156-B1 | HAVING ANTIVIRAL, ANTITUMOR, AND IMMUNOSUPPRESSIVE ACTIVITIES | THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLNOIS | 2002-04-30 | — | — | US | disclosed |
| WO-1998017302-A9 | TOTAL SYNTHESIS OF THE AMINO HIP ANALOGUE OF DIDEMNIN A | — | 1998-10-15 | — | — | WO | disclosed |