Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SSTR1 | P30872 | 1/20 | 0.42 |
| ▸ | SSTR2 | P30874 | 1/20 | 0.42 |
| ▸ | SSTR4 | P31391 | 1/20 | 0.42 |
| ▸ | SSTR3 | P32745 | 1/20 | 0.42 |
| ▸ | SSTR5 | P35346 | 1/20 | 0.42 |
| ▸ | GJB2 | P29033 | 4/20 | 0.42 |
| ▸ | PTPN1 | P18031 | 6/20 | 0.38 |
| ▸ | PTPN2 | P17706 | 3/20 | 0.38 |
| ▸ | NT5E | P21589 | 1/20 | 0.36 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.36 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.35 |
| ▸ | CDC25B | P30305 | 2/20 | 0.35 |
| ▸ | GJA1 | P17302 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13381011 | 0.86 | SSTR1 (0.33) | SSTR1SSTR2SSTR4SSTR3SSTR5 | |
| SCHEMBL6949805 | 0.82 | SSTR1 (0.45) | SSTR1SSTR2SSTR4SSTR3SSTR5 | |
| SCHEMBL6949802 | 0.82 | SSTR1 (0.45) | SSTR1SSTR2SSTR4SSTR3SSTR5 | |
| SCHEMBL13381018 | 0.80 | GJB2 (0.33) | GJB2GJA1 | |
| SCHEMBL1647584 | 0.79 | SSTR1 (0.45) | SSTR1SSTR2SSTR4SSTR3SSTR5 | |
| SCHEMBL10607794 | 0.75 | SSTR1 (0.58) | SSTR1SSTR2SSTR4SSTR3SSTR5 | |
| SCHEMBL8992046 | 0.75 | SSTR1 (0.58) | SSTR1SSTR2SSTR4SSTR3SSTR5 | |
| SCHEMBL10605657 | 0.75 | SSTR1 (0.58) | SSTR1SSTR2SSTR4SSTR3SSTR5 | |
| SCHEMBL8992050 | 0.75 | SSTR1 (0.58) | SSTR1SSTR2SSTR4SSTR3SSTR5 | |
| SCHEMBL10605652 | 0.75 | SSTR1 (0.58) | SSTR1SSTR2SSTR4SSTR3SSTR5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6670338-B1 | Anticoagulants | SANOFI-SYNTHELABO (FR) | 2003-12-30 | — | — | US | disclosed |
| EP-1049706-B1 | NEW PENTASACCHARIDES, THEIR METHODS OF PRODUCTION AND PHARMACEUTICAL COMPOSITIONS CONTAINING SAME | SANOFI SYNTHELABO (FR) | 2003-05-28 | — | — | EP | disclosed |
| US-6534481-B1 | Antithrombin III binding domain consisting of a concatenation of five monosaccharides supporting a total of two carboxylic acid functions and at least four sulpho groups, said domain being directly bound at the non-reducing end by a thrombin | SANOFI-SYNTHELABO (FR) | 2003-03-18 | — | — | US | disclosed |
| EP-0912613-B1 | SYNTHETIC POLYSACCHARIDES, PREPARATION METHOD THEREFOR AND PHARMACEUTICAL COMPOSITIONS CONTAINING SAME | SANOFI SYNTHELABO (FR) | 2002-09-25 | — | — | EP | disclosed |