Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.61 |
| ▸ | NPC1 | O15118 | 3/20 | 0.61 |
| ▸ | RAB9A | P51151 | 3/20 | 0.61 |
| ▸ | MAPT | P10636 | 2/20 | 0.61 |
| ▸ | GAA | P10253 | 1/20 | 0.61 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.60 |
| ▸ | MEN1 | O00255 | 3/20 | 0.60 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.60 |
| ▸ | PKM | P14618 | 1/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.53 |
| ▸ | CTDSP1 | Q9GZU7 | 2/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.53 |
| ▸ | HPGD | P15428 | 1/20 | 0.53 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.53 |
| ▸ | MAOB | P27338 | 2/20 | 0.53 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.52 |
| ▸ | GSK3B | P49841 | 1/20 | 0.51 |
| ▸ | BACE1 | P56817 | 1/20 | 0.51 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.51 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6949177 | 1.00 | KDM4E (0.61) | KDM4ENPC1RAB9AMAPTGAA | |
| SCHEMBL8167160 | 0.82 | KDM4E (0.67) | KDM4ENPC1RAB9AMAPTGAA | |
| SCHEMBL8215173 | 0.80 | MCL1 (0.46) | KDM4ENPC1RAB9AMAPTGAA | |
| SCHEMBL24845094 | 0.78 | KDM4E (0.81) | KDM4ENPC1RAB9AMAPTGAA | |
| SCHEMBL28237091 | 0.78 | KDM4E (0.81) | KDM4ENPC1RAB9AMAPTGAA | |
| SCHEMBL7228423 | 0.77 | NR1H4 (0.58) | KDM4ENPC1RAB9AMAPTGAA | |
| SCHEMBL7006805 | 0.77 | KDM4E (0.56) | KDM4ENPC1RAB9AMAPTGAA | |
| SCHEMBL7006802 | 0.77 | KDM4E (0.56) | KDM4ENPC1RAB9AMAPTGAA | |
| SCHEMBL7031464 | 0.76 | NR1H4 (0.76) | KDM4ENPC1RAB9AMAPTGAA | |
| SCHEMBL5606805 | 0.76 | NR1H4 (0.60) | KDM4ENPC1RAB9AMAPTGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0903343-B1 | Alpha-Substituted phenylpropionic acid derivative and medicine containing the same | SSP CO LTD (JP) | 2003-05-28 | — | — | EP | disclosed |
| EP-0903343-A1 | Alpha-Substituted phenylpropionic acid derivative and medicine containing the same | SSP Co., Ltd. (JP) | 1999-03-24 | — | — | EP | disclosed |