SCHEMBL6949408

SCHEMBL6949408

CCOC(Cc1ccc(OCCN2CCc3ccccc3C2=O)cc1)C(=O)NO

nearest known ligand 0.53

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
PPARG P37231 19/20 0.53
PPARA Q07869 15/20 0.48
PPARD Q03181 3/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6949400 0.90 PPARG (0.54) PPARGPPARAPPARD
SCHEMBL6956717 0.90 PPARG (0.66) PPARGPPARAPPARD
SCHEMBL6948643 0.89 PPARG (0.55) PPARGPPARAPPARD
SCHEMBL6956731 0.83 PPARG (0.46) PPARGPPARAPPARD
SCHEMBL6952072 0.83 PPARG (0.47) PPARGPPARAPPARD
SCHEMBL6954989 0.79 PPARG (0.41) PPARGPPARA
SCHEMBL6948887 0.78 PPARG (0.41) PPARGPPARA
SCHEMBL6952568 0.77 PPARG (0.43) PPARGPPARAPPARD
SCHEMBL6955245 0.77 PPARG (0.40) PPARGPPARAPPARD
SCHEMBL8300709 0.77 DRD3 (0.41) PPARGPPARA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0903343-B1 Alpha-Substituted phenylpropionic acid derivative and medicine containing the same SSP CO LTD (JP) 2003-05-28 EP disclosed
EP-0903343-A1 Alpha-Substituted phenylpropionic acid derivative and medicine containing the same SSP Co., Ltd. (JP) 1999-03-24 EP disclosed