Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 16/20 | 0.40 |
| ▸ | PPARA | Q07869 | 14/20 | 0.39 |
| ▸ | PPARD | Q03181 | 3/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6952568 | 0.83 | PPARG (0.43) | PPARGPPARAPPARD | |
| SCHEMBL6953588 | 0.80 | PPARG (0.39) | PPARGPPARAPPARDTP53 | |
| SCHEMBL6952000 | 0.80 | ITGB3 (0.41) | PPARGPPARAPPARD | |
| SCHEMBL6952249 | 0.78 | PPARG (0.39) | PPARGPPARAPPARD | |
| SCHEMBL6953968 | 0.77 | PPARG (0.35) | PPARGPPARAPPARDMAPTLMNA | |
| SCHEMBL6949408 | 0.77 | PPARG (0.53) | PPARGPPARAPPARD | |
| SCHEMBL6953973 | 0.77 | HPGD (0.35) | PPARGPPARAPPARDMAPTLMNA | |
| SCHEMBL6956731 | 0.77 | PPARG (0.46) | PPARGPPARAPPARD | |
| SCHEMBL6952072 | 0.73 | PPARG (0.47) | PPARGPPARAPPARD | |
| SCHEMBL6952500 | 0.72 | PPARA (0.46) | PPARGPPARAPPARD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0903343-B1 | Alpha-Substituted phenylpropionic acid derivative and medicine containing the same | SSP CO LTD (JP) | 2003-05-28 | — | — | EP | disclosed |
| EP-0903343-A1 | Alpha-Substituted phenylpropionic acid derivative and medicine containing the same | SSP Co., Ltd. (JP) | 1999-03-24 | — | — | EP | disclosed |