Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TACR2 | P21452 | 10/20 | 0.64 |
| ▸ | TACR1 | P25103 | 8/20 | 0.57 |
| ▸ | HRH1 | P35367 | 3/20 | 0.46 |
| ▸ | TACR3 | P29371 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6947096 | 0.87 | TACR2 (0.60) | TACR2TACR1HRH1TACR3 | |
| SCHEMBL8593203 | 0.84 | TACR2 (0.55) | TACR2TACR1HRH1TACR3 | |
| SCHEMBL7954893 | 0.83 | HRH1 (0.55) | TACR2TACR1HRH1TACR3 | |
| SCHEMBL8347632 | 0.81 | TACR2 (0.70) | TACR2TACR1HRH1TACR3 | |
| SCHEMBL8810091 | 0.81 | TACR2 (0.65) | TACR2TACR1HRH1TACR3 | |
| SCHEMBL8886812 | 0.81 | TACR2 (0.65) | TACR2TACR1HRH1TACR3 | |
| SCHEMBL6956796 | 0.80 | TACR2 (0.63) | TACR2TACR1HRH1TACR3 | |
| SCHEMBL6948617 | 0.80 | TACR2 (0.59) | TACR2TACR1HRH1TACR3 | |
| SCHEMBL8291262 | 0.79 | CCR5 (0.51) | TACR2TACR1 | |
| SCHEMBL8292201 | 0.79 | TACR2 (0.57) | TACR2TACR1TACR3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0871623-B1 | 3-AZETIDINYLALKYLPIPERIDINES OR -PYRROLIDINES AS TACHYKININ ANTAGONISTS | PFIZER RES & DEV (IE) | 2003-02-12 | — | — | EP | disclosed |