Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.44 |
| ▸ | MET | P08581 | 1/20 | 0.41 |
| ▸ | OXTR | P30559 | 3/20 | 0.41 |
| ▸ | AVPR1A | P37288 | 3/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | RELA | Q04206 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | NR2F2 | P24468 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.38 |
| ▸ | PTGER1 | P34995 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6949573 | 1.00 | SMN1; SMN2 (0.44) | SMN1; SMN2METOXTRAVPR1AMAPT | |
| SCHEMBL6096889 | 0.90 | SMN1; SMN2 (0.54) | SMN1; SMN2METALDH1A1CYP3A4CYP2C9 | |
| SCHEMBL6096893 | 0.90 | SMN1; SMN2 (0.54) | SMN1; SMN2METALDH1A1CYP3A4CYP2C9 | |
| SCHEMBL6949866 | 0.84 | MET (0.50) | SMN1; SMN2METALDH1A1CYP3A4CYP2C9 | |
| SCHEMBL6949870 | 0.84 | MET (0.50) | SMN1; SMN2METALDH1A1CYP3A4CYP2C9 | |
| Hydrochloric Acid SCHEMBL6952311 | 0.79 | MET (0.48) | SMN1; SMN2METMAPTALDH1A1CYP3A4 | |
| Hydrochloric Acid SCHEMBL6952304 | 0.79 | MET (0.48) | SMN1; SMN2METMAPTALDH1A1CYP3A4 | |
| Hydrochloric Acid SCHEMBL6951847 | 0.79 | MET (0.48) | SMN1; SMN2METALDH1A1CYP3A4CYP2C9 | |
| Hydrochloric Acid SCHEMBL6951891 | 0.79 | MET (0.48) | SMN1; SMN2METMAPTALDH1A1CYP3A4 | |
| Hydrochloric Acid SCHEMBL6951884 | 0.79 | MET (0.48) | SMN1; SMN2METMAPTALDH1A1CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0754682-B9 | AMINOSTILBAZOLE DERIVATIVE AND MEDICINE | NIPPON SHINYAKU CO LTD (JP) | 2003-09-17 | — | — | EP | disclosed |
| EP-0754682-B1 | AMINOSTILBAZOLE DERIVATIVE AND MEDICINE | NIPPON SHINYAKU CO LTD (JP) | 2001-10-17 | — | — | EP | disclosed |
| US-5972976-A | FOR TREATMENT OF VARIOUS MALIGNANT TUMORS; (E)-4-(2-(2-(N-acetyl-N-((p-methoxyphenyl)sulfonyl)amino)phenyl)ethenyl)pyridine-1-oxide for example | NIPPON SHINYAKU COMPANY, LIMITED | 1999-10-26 | — | — | US | disclosed |
| EP-0754682-A1 | AMINOSTILBAZOLE DERIVATIVE AND MEDICINE | NIPPON SHINYAKU COMPANY, LIMITED (JP) | 1997-01-22 | — | — | EP | disclosed |