Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 3/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | KDM5A | P29375 | 1/20 | 0.34 |
| ▸ | KDM7A | Q6ZMT4 | 1/20 | 0.34 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.34 |
| ▸ | PHF8 | Q9UPP1 | 1/20 | 0.34 |
| ▸ | KDM2A | Q9Y2K7 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | HTT | P42858 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4559904 | 1.00 | — | — | |
| SCHEMBL9085332 | 1.00 | SIGMAR1 (0.42) | SIGMAR1CYP1A2KDM5AKDM7AKDM4C | |
| SCHEMBL11673856 | 0.97 | SIGMAR1 (0.39) | SIGMAR1CYP1A2KDM5AKDM7AKDM4C | |
| SCHEMBL9225357 | 0.97 | — | — | |
| SCHEMBL7751427 | 0.89 | SIGMAR1 (0.56) | SIGMAR1CYP1A2KDM5AKDM4CPHF8 | |
| SCHEMBL5883811 | 0.89 | SIGMAR1 (0.56) | SIGMAR1CYP1A2KDM5AKDM4CPHF8 | |
| SCHEMBL5883750 | 0.89 | SIGMAR1 (0.50) | SIGMAR1CYP1A2KDM5AKDM4CPHF8 | |
| SCHEMBL4807841 | 0.88 | SIGMAR1 (0.40) | SIGMAR1KDM5AKDM7AKDM4CPHF8 | |
| SCHEMBL4807846 | 0.88 | SIGMAR1 (0.40) | SIGMAR1KDM5AKDM7AKDM4CPHF8 | |
| SCHEMBL281878 | 0.88 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0639189-B1 | PYRIDYLPYRIMIDINES, A METHOD OF PREPARING THEM, AND THEIR USE IN LIQUID-CRYSTAL MIXTURES | AVENTIS RES & TECH GMBH & CO (DE) | 2003-02-19 | — | — | EP | disclosed |
| US-5443754-A | Pyridylpyrimidines, a process for their preparation and their use in liquid-crystalline mixtures | HOECHST AKTIENGESELLSCHAFT (DE) | 1995-08-22 | — | — | US | disclosed |
| US-5439612-A | Ferroelectric switches, displaying | HOECHST AKTIENGESELLSCHAFT (DE) | 1995-08-08 | — | — | US | disclosed |
| EP-0639189-A1 | PYRIDYLPYRIMIDINES, A METHOD OF PREPARING THEM, AND THEIR USE IN LIQUID-CRYSTAL MIXTURES | HOECHST AKTIENGESELLSCHAFT (DE) | 1995-02-22 | — | — | EP | disclosed |
| EP-0639189-A4 | PYRIDYLPYRIMIDINES, A METHOD OF PREPARING THEM, AND THEIR USE IN LIQUID-CRYSTAL MIXTURES. | AVENTIS RES & TECH GMBH & CO (DE) | 1993-09-17 | — | — | EP | disclosed |
| US-5200521-A | Ferroelectricity; electrooptical switching and display devices | HOECHST AKTIENGESELLSCHAFT (DE) | 1993-04-06 | — | — | US | disclosed |
| WO-1992012974-A1 | PYRIDYLPYRIMIDINES, A METHOD OF PREPARING THEM, AND THEIR USE IN LIQUID-CRYSTAL MIXTURES | HOECHST AKTIENGESELLSCHAFT (DE) | 1992-08-06 | — | — | WO | disclosed |
| EP-0477901-A2 | Cyclohexylphenylpyrimidines, process for their preparation und their use in liquid crystal compositions | HOECHST AKTIENGESELLSCHAFT (DE) | 1992-04-01 | — | — | EP | disclosed |