Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 19/20 | 0.66 |
| ▸ | ITGA2B | P08514 | 19/20 | 0.66 |
| ▸ | ITGAV | P06756 | 3/20 | 0.46 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6945833 | 0.89 | ITGB3 (0.72) | ITGB3ITGA2BITGAVROCK2 | |
| SCHEMBL6674305 | 0.88 | ITGB3 (0.69) | ITGB3ITGA2BITGAVROCK2 | |
| SCHEMBL7438405 | 0.83 | ITGB3 (0.67) | ITGB3ITGA2BITGAVROCK2 | |
| SCHEMBL6953547 | 0.80 | ITGB3 (0.67) | ITGB3ITGA2BITGAV | |
| SCHEMBL6945074 | 0.79 | ITGB3 (1.00) | ITGB3ITGA2B | |
| SCHEMBL6944818 | 0.79 | ITGB3 (1.00) | ITGB3ITGA2B | |
| SCHEMBL6948600 | 0.78 | ITGB3 (0.61) | ITGB3ITGA2BITGAV | |
| SCHEMBL6948601 | 0.78 | ITGB3 (0.61) | ITGB3ITGA2BITGAV | |
| SCHEMBL6947924 | 0.74 | ITGB3 (0.74) | ITGB3ITGA2BITGAV | |
| SCHEMBL6947929 | 0.74 | ITGB3 (0.74) | ITGB3ITGA2BITGAV |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0674623-B1 | BICYCLIC FIBRINOGEN ANTAGONISTS | SMITHKLINE BEECHAM CORP (US) | 2003-04-09 | — | — | EP | disclosed |
| US-6403578-B1 | ANTICOAGULANTS, CARDIOVASCULAR DISORDERS | SMITHKLINE BEECHAM CORPORATION | 2002-06-11 | — | — | US | disclosed |
| EP-0674623-A1 | BICYCLIC FIBRINOGEN ANTAGONISTS | SMITHKLINE BEECHAM CORPORATION (US) | 1995-10-04 | — | — | EP | disclosed |
| WO-1994014776-A2 | BICYCLIC FIBRINOGEN ANTAGONISTS | SMITHKLINE BEECHAM CORPORATION (US) | 1994-07-07 | — | — | WO | disclosed |