SCHEMBL6950188

SCHEMBL6950188

Cc1nc2ccccc2n1C(=O)NC(=O)c1ccc2c(c1)CN(C)C(=O)C(CC(=O)O)N2

nearest known ligand 0.64

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
ITGB3 P05106 20/20 0.64
ITGAV P06756 20/20 0.64
ITGA2B P08514 12/20 0.62

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8468848 0.79 ITGB3 (0.70) ITGB3ITGAVITGA2B
SCHEMBL8468835 0.79 ITGB3 (0.70) ITGB3ITGAVITGA2B
SCHEMBL7329758 0.78 ITGB3 (1.00) ITGB3ITGAVITGA2B
SCHEMBL7074854 0.78 ITGB3 (0.68) ITGB3ITGAVITGA2B
SCHEMBL6950176 0.77 ITGB3 (0.62) ITGB3ITGAVITGA2B
SCHEMBL6941347 0.76 ITGB3 (1.00) ITGB3ITGAVITGA2B
SCHEMBL7333365 0.76 ITGB3 (1.00) ITGB3ITGAVITGA2B
SCHEMBL8469034 0.76 ITGB3 (0.66) ITGB3ITGAVITGA2B
SCHEMBL8360041 0.76 ITGB3 (0.63) ITGB3ITGAVITGA2B
SCHEMBL7796007 0.76 ITGB3 (0.66) ITGB3ITGAVITGA2B

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0946180-A4 METHOD FOR STIMULATING BONE FORMATION SMITHKLINE BEECHAM CORP (US) 2003-07-23 EP claimed
EP-0946180-A1 METHOD FOR STIMULATING BONE FORMATION SMITHKLINE BEECHAM CORPORATION (US) 1999-10-06 EP claimed
WO-1998015278-A1 METHOD FOR STIMULATING BONE FORMATION SMITHKLINE BEECHAM CORPORATION (US) 1998-04-16 WO claimed
EP-0946180-A4 METHOD FOR STIMULATING BONE FORMATION SMITHKLINE BEECHAM CORP (US) 2003-07-23 EP disclosed
EP-0946180-A1 METHOD FOR STIMULATING BONE FORMATION SMITHKLINE BEECHAM CORPORATION (US) 1999-10-06 EP disclosed
WO-1998015278-A1 METHOD FOR STIMULATING BONE FORMATION SMITHKLINE BEECHAM CORPORATION (US) 1998-04-16 WO disclosed