Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOTUM | Q6P988 | 8/20 | 0.36 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.35 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.35 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.35 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.34 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.34 |
| ▸ | CASP3 | P42574 | 1/20 | 0.32 |
| ▸ | IDO1 | P14902 | 1/20 | 0.32 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.32 |
| ▸ | HTR3B | O95264 | 1/20 | 0.32 |
| ▸ | HTR3A | P46098 | 1/20 | 0.32 |
| ▸ | HTR3D | Q70Z44 | 1/20 | 0.32 |
| ▸ | HTR3C | Q8WXA8 | 1/20 | 0.32 |
| ▸ | KDR | P35968 | 1/20 | 0.32 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.31 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.31 |
| ▸ | MPL | P40238 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30355198 | 1.00 | NOTUM (0.36) | NOTUMTRPA1TRPM8TRPV1CYP11B1 | |
| SCHEMBL7786072 | 0.85 | MPL (0.35) | NOTUMTRPA1TRPM8TRPV1CYP11B1 | |
| SCHEMBL28454953 | 0.84 | NOTUM (0.35) | NOTUMTRPA1TRPM8TRPV1CYP11B1 | |
| SCHEMBL21670482 | 0.84 | NOTUM (0.35) | NOTUMTRPA1TRPM8TRPV1CYP11B1 | |
| SCHEMBL30285322 | 0.84 | NOTUM (0.35) | NOTUMTRPA1TRPM8TRPV1CYP11B1 | |
| SCHEMBL8114322 | 0.77 | CYP3A4 (0.37) | NOTUM | |
| SCHEMBL8532334 | 0.77 | HPGD (0.35) | NOTUMTRPA1TRPM8CYP11B1CYP11B2 | |
| SCHEMBL6946317 | 0.77 | MAPT (0.35) | NOTUMTRPA1TRPM8TRPV1IDO1 | |
| SCHEMBL8659559 | 0.73 | TRPA1 (0.35) | NOTUMTRPA1ALOX15 | |
| SCHEMBL11602223 | 0.72 | NOTUM (0.44) | NOTUMIDO1HTR3EHTR3BHTR3A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116003314-A | Method for purifying 2-fluoro-3-chloro-5-trifluoromethyl pyridine by utilizing microreactor | 内蒙古佳瑞米精细化工有限公司 | 2023-04-25 | — | — | CN | claimed |
| CN-116003314-A | Method for purifying 2-fluoro-3-chloro-5-trifluoromethyl pyridine by utilizing microreactor | 内蒙古佳瑞米精细化工有限公司 | 2023-04-25 | — | — | CN | disclosed |
| EP-0846113-B1 | 1-(PYRIDYL)-PYRAZOLS AND THEIR USE AS HERBICIDES | BASF AG (DE) | 2003-01-29 | — | — | EP | disclosed |
| EP-0759429-B1 | Substituted trifluormethylpyridines useful as intermediates for herbicidal 1-(pyridyl)-pyrazoles | BASF AG (DE) | 2001-10-24 | — | — | EP | disclosed |
| US-6107253-A | GOOD HERBICIDAL ACTION AND ARE TOLERABLE IN CROPS SUCH AS WHEAT OR RICE | BASF AKTIENGESELLSCHAFT (DE) | 2000-08-22 | — | — | US | disclosed |
| US-5849920-A | Substituted trifluoromethylpyridines | BASF AKTIENGESELLSCHAFT (DE) | 1998-12-15 | — | — | US | disclosed |
| EP-0846113-A1 | 1-(PYRIDYL)-PYRAZOLS AND THEIR USE AS HERBICIDES | BASF AKTIENGESELLSCHAFT (DE) | 1998-06-10 | — | — | EP | disclosed |
| US-5750705-A | HERBICIDES | BASF AKTIENGESELLSCHAFT (DE) | 1998-05-12 | — | — | US | disclosed |
| WO-1997007114-A1 | 1-(PYRIDYL)-PYRAZOLS AND THEIR USE AS HERBICIDES | BASF AKTIENGESELLSCHAFT (DE) | 1997-02-27 | — | — | WO | disclosed |
| EP-0759429-A1 | Substituted trifluormethylpyridines useful as intermediates for herbicidal 1-(pyridyl)-pyrazoles | BASF Aktiengesellschaft (DE) | 1997-02-26 | — | — | EP | disclosed |
| EP-0603299-A1 | SEMI-PERMEABLE MEMBRANES DERIVED FROM REACTIVE OLIGOMERS | THE DOW CHEMICAL COMPANY (US) | 1994-06-29 | — | — | EP | disclosed |
| WO-1993005866-A1 | SEMI-PERMEABLE MEMBRANES DERIVED FROM REACTIVE OLIGOMERS | THE DOW CHEMICAL COMPANY (US) | 1993-04-01 | — | — | WO | disclosed |
| US-5156656-A | Gas separation | THE DOW CHEMICAL COMPANY (US) | 1992-10-20 | — | — | US | disclosed |