Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN1 | P18031 | 19/20 | 0.79 |
| ▸ | PTPRC | P08575 | 5/20 | 0.79 |
| ▸ | PTPN2 | P17706 | 5/20 | 0.50 |
| ▸ | PTPN6 | P29350 | 4/20 | 0.46 |
| ▸ | PTPRB | P23467 | 3/20 | 0.46 |
| ▸ | PTPN11 | Q06124 | 3/20 | 0.46 |
| ▸ | CDC25A | P30304 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6944118 | 0.91 | PTPN1 (0.81) | PTPN1PTPRCPTPN2PTPN6PTPRB | |
| SCHEMBL6951489 | 0.89 | PTPN1 (1.00) | PTPN1PTPRCPTPN2PTPN6PTPRB | |
| SCHEMBL6952067 | 0.89 | PTPN1 (1.00) | PTPN1PTPRCPTPN2PTPN6PTPRB | |
| SCHEMBL6952150 | 0.86 | PTPN1 (1.00) | PTPN1PTPRCPTPN2PTPN6PTPRB | |
| SCHEMBL6951017 | 0.86 | PTPN1 (1.00) | PTPN1PTPRCPTPN2PTPN6PTPRB | |
| SCHEMBL6944081 | 0.84 | PTPN1 (0.64) | PTPN1PTPRCPTPN2PTPN6PTPRB | |
| SCHEMBL7888258 | 0.84 | PTPN1 (0.81) | PTPN1PTPRCPTPN2PTPN6PTPRB | |
| SCHEMBL6946506 | 0.84 | PTPN1 (0.80) | PTPN1PTPRCPTPN2PTPN6PTPRB | |
| SCHEMBL6949886 | 0.84 | PTPN1 (1.00) | PTPN1PTPRCPTPN2PTPN6PTPRB | |
| SCHEMBL6943702 | 0.84 | PTPN1 (0.88) | PTPN1PTPRCPTPN2PTPN6PTPRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1115729-B1 | PHOSPHONIC ACID DERIVATIVES AS INHIBITORS OF PTP-1B | MERCK FROSST CANADA INC (CA) | 2003-02-19 | — | — | EP | claimed |