Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.49 |
| ▸ | EED | O75530 | 3/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | GBA1 | P04062 | 1/20 | 0.44 |
| ▸ | CHRNB2 | P17787 | 2/20 | 0.44 |
| ▸ | CHRNB4 | P30926 | 2/20 | 0.44 |
| ▸ | CHRNA3 | P32297 | 2/20 | 0.44 |
| ▸ | CHRNA4 | P43681 | 2/20 | 0.44 |
| ▸ | CPN1 | P15169 | 1/20 | 0.43 |
| ▸ | CPB2 | Q96IY4 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Mandelic Acid SCHEMBL23121138 | 0.92 | KMT2A (0.44) | KMT2AEEDLMNAMAPK1CHRNB2 | |
| Mandelic Acid SCHEMBL5220523 | 0.92 | KMT2A (0.44) | KMT2AEEDLMNAMAPK1CHRNB2 | |
| Mandelic Acid SCHEMBL6974418 | 0.92 | KMT2A (0.44) | KMT2AEEDLMNAMAPK1CHRNB2 | |
| Mandelic Acid SCHEMBL6264513 | 0.92 | KMT2A (0.44) | KMT2AEEDLMNAMAPK1CHRNB2 | |
| SCHEMBL8547993 | 0.83 | EED (0.61) | KMT2AEEDGBA1CHRNB2CHRNB4 | |
| SCHEMBL1761058 | 0.83 | EED (0.61) | KMT2AEEDGBA1CHRNB2CHRNB4 | |
| SCHEMBL3473180 | 0.83 | EED (0.61) | KMT2AEEDGBA1CHRNB2CHRNB4 | |
| Hydrochloric Acid SCHEMBL3914926 | 0.82 | EED (0.60) | KMT2AEEDGBA1CHRNB2CHRNB4 | |
| Hydrochloric Acid SCHEMBL7068731 | 0.80 | EED (0.58) | KMT2AEEDGBA1CHRNB2CHRNB4 | |
| Mandelic Acid SCHEMBL7303904 | 0.80 | KMT2A (0.50) | KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0993458-B1 | 3-BENZYLPIPERIDINE | MERCK PATENT GMBH (DE) | 2003-04-09 | — | — | EP | disclosed |
| US-6333339-B1 | CENTRAL SYSTEM DISORDERS, SCHIZOPHRENIA AND COGNITION ACTIVATORS | MERCK PATENT GELLSCHAFT MIT BESCHRANKTER (DE) | 2001-12-25 | — | — | US | disclosed |
| EP-0993458-A1 | 3-BENZYLPIPERIDINE | MERCK PATENT GmbH (DE) | 2000-04-19 | — | — | EP | disclosed |
| WO-1998057953-A1 | 3-BENZYLPIPERIDINE | MERCK PATENT GMBH (DE) | 1998-12-23 | — | — | WO | disclosed |