Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 3/20 | 0.59 |
| ▸ | RAB9A | P51151 | 3/20 | 0.59 |
| ▸ | PKM | P14618 | 2/20 | 0.59 |
| ▸ | MITF | O75030 | 1/20 | 0.59 |
| ▸ | PPARA | Q07869 | 14/20 | 0.52 |
| ▸ | PPARG | P37231 | 14/20 | 0.52 |
| ▸ | PPARD | Q03181 | 2/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
| ▸ | MMP2 | P08253 | 1/20 | 0.45 |
| ▸ | MMP3 | P08254 | 1/20 | 0.45 |
| ▸ | MMP9 | P14780 | 1/20 | 0.45 |
| ▸ | MMP13 | P45452 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8133366 | 0.95 | NPC1 (0.57) | NPC1RAB9APKMMITFPPARA | |
| SCHEMBL8125999 | 0.93 | NPC1 (0.59) | NPC1RAB9APKMMITFPPARA | |
| SCHEMBL6947575 | 0.92 | PPARG (0.63) | NPC1RAB9APKMMITFPPARA | |
| SCHEMBL6954546 | 0.91 | NPC1 (0.59) | NPC1RAB9APKMMITFPPARA | |
| SCHEMBL6953984 | 0.89 | NPC1 (0.57) | NPC1RAB9APKMMITFPPARA | |
| SCHEMBL8131914 | 0.89 | NPC1 (0.57) | NPC1RAB9APKMMITFPPARA | |
| SCHEMBL8124004 | 0.89 | PPARA (0.47) | NPC1RAB9APKMMITFPPARA | |
| SCHEMBL8133266 | 0.89 | NPC1 (0.61) | NPC1RAB9APKMMITFPPARA | |
| SCHEMBL8118173 | 0.88 | PPARA (0.54) | NPC1RAB9APKMMITFPPARA | |
| SCHEMBL8131977 | 0.88 | PPARA (0.46) | NPC1RAB9APKMMITFPPARA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1051403-A1 | NOVEL ALKANOIC ACIDS AND THEIR USE IN MEDICINE, PROCESS FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | DR. REDDY'S RESEARCH FOUNDATION (IN) | 2000-11-15 | — | — | EP | claimed |
| WO-1999038850-A1 | NOVEL ALKANOIC ACIDS AND THEIR USE IN MEDICINE, PROCESS FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | DR. REDDY'S RESEARCH FOUNDATION (IN) | 1999-08-05 | — | — | WO | claimed |
| EP-0903343-B1 | Alpha-Substituted phenylpropionic acid derivative and medicine containing the same | SSP CO LTD (JP) | 2003-05-28 | — | — | EP | disclosed |
| EP-0903343-A1 | Alpha-Substituted phenylpropionic acid derivative and medicine containing the same | SSP Co., Ltd. (JP) | 1999-03-24 | — | — | EP | disclosed |