Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 4/20 | 0.59 |
| ▸ | RAB9A | P51151 | 4/20 | 0.59 |
| ▸ | PKM | P14618 | 2/20 | 0.59 |
| ▸ | MITF | O75030 | 1/20 | 0.59 |
| ▸ | PPARG | P37231 | 12/20 | 0.52 |
| ▸ | PPARA | Q07869 | 12/20 | 0.52 |
| ▸ | PPARD | Q03181 | 3/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
| ▸ | MMP2 | P08253 | 1/20 | 0.45 |
| ▸ | MMP3 | P08254 | 1/20 | 0.45 |
| ▸ | MMP9 | P14780 | 1/20 | 0.45 |
| ▸ | MMP13 | P45452 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6956497 | 0.94 | NPC1 (0.58) | NPC1RAB9APKMMITFPPARG | |
| SCHEMBL6947575 | 0.92 | PPARG (0.63) | NPC1RAB9APKMMITFPPARG | |
| SCHEMBL6950499 | 0.91 | NPC1 (0.59) | NPC1RAB9APKMMITFPPARG | |
| SCHEMBL6955885 | 0.91 | NPC1 (0.61) | NPC1RAB9APKMMITFPPARG | |
| SCHEMBL6953984 | 0.89 | NPC1 (0.57) | NPC1RAB9APKMMITFPPARG | |
| SCHEMBL6956051 | 0.89 | NPC1 (0.52) | NPC1RAB9APKMMITFPPARG | |
| SCHEMBL6952445 | 0.89 | NPC1 (0.59) | NPC1RAB9APKMMITFPPARG | |
| SCHEMBL6956847 | 0.89 | NPC1 (0.67) | NPC1RAB9APKMMITFPPARG | |
| SCHEMBL6950676 | 0.88 | PPARA (0.46) | NPC1RAB9APKMMITFPPARG | |
| SCHEMBL7074163 | 0.87 | NPC1 (0.67) | NPC1RAB9APKMMITFPPARG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-11158144-A | — | — | None | — | — | JP | disclosed |
| EP-0903343-B1 | Alpha-Substituted phenylpropionic acid derivative and medicine containing the same | SSP CO LTD (JP) | 2003-05-28 | — | — | EP | disclosed |
| JP-H11158144-A | ALPHA-SUBSTITUTED PHENYLPROPIONIC ACID DERIVATIVE AND MEDICINE CONTAINING THE SAME | SS PHARMACEUT CO LTD | 1999-06-15 | — | — | JP | disclosed |
| EP-0903343-A1 | Alpha-Substituted phenylpropionic acid derivative and medicine containing the same | SSP Co., Ltd. (JP) | 1999-03-24 | — | — | EP | disclosed |