Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.46 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.40 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.40 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.40 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.40 |
| ▸ | NCEH1 | Q6PIU2 | 7/20 | 0.39 |
| ▸ | PKM | P14618 | 2/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | BCHE | P06276 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3866066 | 0.85 | TSHR (0.40) | TSHRCHRNB2CHRNB4CHRNA3CHRNA4 | |
| SCHEMBL3864617 | 0.81 | PPARG (0.45) | TSHRCHRNB2CHRNB4CHRNA3CHRNA4 | |
| SCHEMBL3865746 | 0.79 | TSHR (0.43) | TSHRCHRNB2CHRNB4CHRNA3CHRNA4 | |
| SCHEMBL3874630 | 0.78 | KDM4E (0.47) | NPC1RAB9AKMT2A | |
| SCHEMBL3866012 | 0.77 | TSHR (0.38) | TSHRNCEH1PKMNPC1RAB9A | |
| SCHEMBL6950634 | 0.76 | RAB9A (0.53) | CHRNB2CHRNB4CHRNA3CHRNA4PKM | |
| SCHEMBL5199111 | 0.75 | NCEH1 (0.40) | TSHRNCEH1PKMNPC1RAB9A | |
| SCHEMBL4463979 | 0.75 | HSD17B10 (0.43) | TSHRNPC1RAB9AKMT2ABCHE | |
| SCHEMBL3871280 | 0.75 | NCEH1 (0.38) | TSHRNCEH1BCHE | |
| Dimethylformamide SCHEMBL6715442 | 0.74 | KDM4E (0.43) | NPC1RAB9AKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1362844-A1 | BENZYLAMINE ANALOGUE | Sankyo Company, Limited (JP) | 2003-11-19 | — | — | EP | disclosed |