Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARA | Q07869 | 16/20 | 0.46 |
| ▸ | NPC1 | O15118 | 2/20 | 0.44 |
| ▸ | RAB9A | P51151 | 2/20 | 0.44 |
| ▸ | MITF | O75030 | 1/20 | 0.44 |
| ▸ | PKM | P14618 | 1/20 | 0.44 |
| ▸ | PPARG | P37231 | 15/20 | 0.44 |
| ▸ | PPARD | Q03181 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | PGR | P06401 | 1/20 | 0.39 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.39 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.39 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.39 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.39 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.39 |
| ▸ | PDE4A | P27815 | 1/20 | 0.39 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.39 |
| ▸ | DRD3 | P35462 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8124004 | 0.92 | PPARA (0.47) | PPARANPC1RAB9AMITFPKM | |
| SCHEMBL8116567 | 0.92 | PPARA (0.53) | PPARANPC1RAB9AMITFPKM | |
| SCHEMBL6954546 | 0.88 | NPC1 (0.59) | PPARANPC1RAB9AMITFPKM | |
| SCHEMBL8118173 | 0.84 | PPARA (0.54) | PPARANPC1RAB9AMITFPKM | |
| SCHEMBL8131011 | 0.83 | PPARA (0.53) | PPARANPC1RAB9AMITFPKM | |
| SCHEMBL8131977 | 0.83 | PPARA (0.46) | PPARANPC1RAB9AMITFPKM | |
| SCHEMBL8123609 | 0.83 | PPARA (0.53) | PPARANPC1RAB9AMITFPKM | |
| SCHEMBL8124015 | 0.82 | PPARA (0.52) | PPARAPPARGPPARD | |
| SCHEMBL8125818 | 0.82 | PPARA (0.63) | PPARANPC1RAB9AMITFPKM | |
| SCHEMBL6956497 | 0.82 | NPC1 (0.58) | PPARANPC1RAB9AMITFPKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0903343-B1 | Alpha-Substituted phenylpropionic acid derivative and medicine containing the same | SSP CO LTD (JP) | 2003-05-28 | — | — | EP | disclosed |
| EP-0903343-A1 | Alpha-Substituted phenylpropionic acid derivative and medicine containing the same | SSP Co., Ltd. (JP) | 1999-03-24 | — | — | EP | disclosed |