Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 5/20 | 0.41 |
| ▸ | DRD3 | P35462 | 11/20 | 0.40 |
| ▸ | DRD2 | P14416 | 4/20 | 0.40 |
| ▸ | DRD4 | P21917 | 1/20 | 0.40 |
| ▸ | DRD1 | P21728 | 5/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | GRM5 | P41594 | 1/20 | 0.39 |
| ▸ | PPARA | Q07869 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6956670 | 0.88 | PPARG (0.43) | PPARGDRD3DRD2DRD4DRD1 | |
| SCHEMBL6950469 | 0.81 | DRD3 (0.46) | PPARGDRD3DRD2DRD4DRD1 | |
| SCHEMBL6949400 | 0.78 | PPARG (0.54) | PPARGPPARA | |
| SCHEMBL6956717 | 0.76 | PPARG (0.66) | PPARGPPARA | |
| SCHEMBL6948643 | 0.75 | PPARG (0.55) | PPARGPPARA | |
| SCHEMBL6955902 | 0.74 | PPARG (0.42) | PPARGMEN1KMT2APPARA | |
| SCHEMBL6949408 | 0.74 | PPARG (0.53) | PPARGPPARA | |
| SCHEMBL6952012 | 0.70 | PPARG (0.38) | PPARGPPARA | |
| SCHEMBL31134854 | 0.69 | GRM5 (0.64) | DRD3DRD2DRD4DRD1GRM5 | |
| SCHEMBL5811132 | 0.69 | GRM5 (0.64) | DRD3DRD2DRD4DRD1GRM5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0903343-B1 | Alpha-Substituted phenylpropionic acid derivative and medicine containing the same | SSP CO LTD (JP) | 2003-05-28 | — | — | EP | disclosed |
| EP-0903343-A1 | Alpha-Substituted phenylpropionic acid derivative and medicine containing the same | SSP Co., Ltd. (JP) | 1999-03-24 | — | — | EP | disclosed |