SCHEMBL69507

SCHEMBL69507

C=CC(=O)OC1CC(C)(C)N(C)C(C)(C)C1

nearest known ligand 0.33

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
TSHR P16473 3/20 0.33
KMT2A Q03164 1/20 0.33
GAA P10253 1/20 0.33
HTT P42858 1/20 0.33
ALDH1A1 P00352 1/20 0.32
ESR1 P03372 1/20 0.32
HSD17B10 Q99714 1/20 0.32
CYP2D6 P10635 1/20 0.30
NFKB1 P19838 1/20 0.30
CYP2C19 P33261 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Ethylene SCHEMBL11193217 0.98 TSHR (0.33) TSHRKMT2AGAAHTTALDH1A1
SCHEMBL10986965 0.91 GAA (0.41) GAA
SCHEMBL1053833 0.86 GAA (0.44) TSHRKMT2AGAAHTTALDH1A1
SCHEMBL3191892 0.86 TSHR (0.33) TSHRKMT2AGAAHTTALDH1A1
SCHEMBL8790619 0.85 TSHR (0.35) TSHRKMT2AGAAHTTALDH1A1
SCHEMBL10707940 0.85 TSHR (0.35) TSHRKMT2AGAAHTTALDH1A1
SCHEMBL8790610 0.85 TSHR (0.35) TSHRKMT2AGAAHTTALDH1A1
SCHEMBL8850033 0.84 TSHR (0.33) TSHRKMT2AGAAHTTALDH1A1
SCHEMBL1685817 0.84 TSHR (0.33) TSHRKMT2AGAAHTTALDH1A1
SCHEMBL1685794 0.84 TSHR (0.33) TSHRKMT2AGAAHTTALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 459 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9555160-B2 Process for producing high molecular weight polyethylene DSM IP ASSETS B.V. (NL) 2017-01-31 US claimed
US-20160184476-A1 PROCESS FOR PRODUCING HIGH MOLECULAR WEIGHT POLYETHYLENE DSM IP ASSETS BV (NL) 2016-06-30 US claimed
CN-105601792-A Preparation method of controllable molecular weight copolymerized hindered amine light stabilizer UNIV SICHUAN 2016-05-25 CN claimed
US-9290629-B2 Process for producing high molecular weight polyethylene DSM IP ASSETS B.V. (NL) 2016-03-22 US claimed
CN-102558428-B Hindered amine light stabilizer with toughening effect and preparation method thereof UNIV SICHUAN 2014-05-07 CN claimed
US-20130168128-A1 SUN-LIGHT RESISTANT SELF-LUBRICATED INSULATED CONDUCTOR VIAKABLE, S. A. DE C. V. (MX) 2013-07-04 US claimed
CN-102558428-A Hindered amine light stabilizer with toughening effect and preparation method thereof SICHUAN UNIVERISITY 2012-07-11 CN claimed
EP-1571177-A1 Elastomer with improved weather resistance DSM IP Assets B.V. (NL) 2005-09-07 EP claimed
US-20040209016-A1 Recording medium excellent in light-resistance and method for production thereof MITSUI CHEMICALS, INC. (JP) 2004-10-21 US claimed
EP-1418056-A1 RECORDING MEDIUM EXCELLENT IN LIGHT−RESISTANCE AND METHOD FOR PRODUCTION THEREOF Mitsui Chemicals, Inc. (JP) 2004-05-12 EP claimed
EP-0499581-B1 Stabilized polymer composition CIBA GEIGY AG (CH) 1997-07-09 EP claimed
EP-0468418-B1 Ethylene copolymer and method of producing same MITSUBISHI PETROCHEMICAL CO (JP) 1995-05-03 EP claimed
EP-0479725-B1 Stabilized styrene copolymers containing elastomer particles CIBA GEIGY AG (CH) 1995-04-26 EP claimed
US-5194465-A Photostability, graft polymers, unsaturated hindered amine modifier CIBA-GEIGY CORPORATION (US) 1993-03-16 US claimed
US-5182349-A 2,2,6,6-Tetramethyl-4-piperidinyl (Meth)Acrylate MITSUBISHI PETROCHEMICAL COMPANY, LTD. (JP) 1993-01-26 US claimed
US-5135986-A Graft polymers of styrene or A-methylstyrene and a comonomer on a core of elastomer modified by a steric hindered unsaturated 2,2,6,6-tetramethylpiperidine compoune; photostability CIBA-GEIGY CORPORATION (US) 1992-08-04 US claimed
EP-0479725-A2 Stabilized styrene copolymers containing elastomer particles CIBA-GEIGY AG (CH) 1992-04-08 EP claimed
EP-0468418-A1 Ethylene copolymer and method of producing same MITSUBISHI PETROCHEMICAL CO., LTD. (JP) 1992-01-29 EP claimed
US-4957953-A MONO-AND POLYTETRAMETHYLPIPERIDINE ESTERS ADEKA ARGUS CHEMICAL CO., LTD. (JP) 1990-09-18 US claimed
EP-0337431-A2 Stabilized styrene copolymer comprising elastomer particles CIBA-GEIGY AG (CH) 1989-10-18 EP claimed