Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP3 | P08254 | 15/20 | 0.78 |
| ▸ | MMP1 | P03956 | 5/20 | 0.78 |
| ▸ | MMP2 | P08253 | 1/20 | 0.57 |
| ▸ | CA1 | P00915 | 4/20 | 0.57 |
| ▸ | CA9 | Q16790 | 3/20 | 0.57 |
| ▸ | CA2 | P00918 | 3/20 | 0.57 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.54 |
| ▸ | LMNA | P02545 | 1/20 | 0.54 |
| ▸ | POLB | P06746 | 1/20 | 0.54 |
| ▸ | MAPT | P10636 | 1/20 | 0.54 |
| ▸ | PKM | P14618 | 1/20 | 0.54 |
| ▸ | HPGD | P15428 | 1/20 | 0.54 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.54 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.54 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.54 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.54 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6950729 | 1.00 | MMP3 (0.78) | MMP3MMP1MMP2CA1CA9 | |
| SCHEMBL7332687 | 0.88 | MMP3 (0.76) | MMP3MMP1MMP2CA1CA9 | |
| SCHEMBL6956826 | 0.88 | MMP3 (1.00) | MMP3MMP1MMP2 | |
| SCHEMBL6955435 | 0.88 | MMP3 (0.76) | MMP3MMP1MMP2CA1CA9 | |
| SCHEMBL6956824 | 0.88 | MMP3 (1.00) | MMP3MMP1MMP2 | |
| SCHEMBL6957782 | 0.82 | MMP3 (0.71) | MMP3MMP1MMP2CA1CA9 | |
| SCHEMBL6956258 | 0.80 | MMP3 (0.71) | MMP3MMP1MMP2CA1CA9 | |
| SCHEMBL2679911 | 0.79 | MMP3 (1.00) | MMP3MMP1MMP2 | |
| SCHEMBL6956147 | 0.79 | MMP3 (1.00) | MMP3MMP1MMP2 | |
| SCHEMBL10118131 | 0.79 | MMP3 (1.00) | MMP3MMP1MMP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0900211-B1 | THIADIAZOLYL(THIO)UREAS USEFUL AS MATRIX METALLOPROTEASE INHIBITORS | UPJOHN CO (US) | 2003-07-02 | — | — | EP | claimed |