Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.54 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.54 |
| ▸ | CHRNA7 | P36544 | 2/20 | 0.50 |
| ▸ | PKM | P14618 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.47 |
| ▸ | CHRNB2 | P17787 | 3/20 | 0.46 |
| ▸ | CHRNA4 | P43681 | 3/20 | 0.46 |
| ▸ | TBXAS1 | P24557 | 4/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | HRH1 | P35367 | 2/20 | 0.45 |
| ▸ | ESR1 | P03372 | 1/20 | 0.44 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10034621 | 1.00 | TDP1 (0.54) | TDP1L3MBTL1CHRNA7PKMKMT2A | |
| Ammonia Solution, Strong SCHEMBL6014385 | 0.98 | TDP1 (0.53) | TDP1L3MBTL1CHRNA7PKMKMT2A | |
| SCHEMBL9522636 | 0.90 | TDP1 (0.60) | TDP1L3MBTL1CHRNA7PKMKMT2A | |
| SCHEMBL7803183 | 0.90 | TDP1 (0.60) | TDP1L3MBTL1CHRNA7PKMKMT2A | |
| SCHEMBL5016747 | 0.89 | CHRNA7 (0.57) | TDP1L3MBTL1CHRNA7CYP2A6TBXAS1 | |
| SCHEMBL6950222 | 0.84 | CHRNA7 (0.52) | TDP1L3MBTL1CHRNA7CYP2A6TBXAS1 | |
| SCHEMBL7831473 | 0.84 | CHRNA7 (0.52) | TDP1L3MBTL1CHRNA7CYP2A6TBXAS1 | |
| SCHEMBL6950227 | 0.84 | CHRNA7 (0.52) | TDP1L3MBTL1CHRNA7CYP2A6TBXAS1 | |
| SCHEMBL6946868 | 0.83 | CHRNA7 (0.50) | TDP1L3MBTL1CHRNA7CYP2A6TBXAS1 | |
| SCHEMBL8477435 | 0.83 | CHRNA7 (0.50) | TDP1L3MBTL1CHRNA7CYP2A6TBXAS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102574845-A | 1h-imidazo[4,5-c]quinolinone derivatives | NOVARTIS AG | 2012-07-11 | — | — | CN | disclosed |
| EP-1074544-B1 | Process for production of 3-(3-pyridyl)-1-propanol derivatives | KANEKA CORP (JP) | 2003-08-27 | — | — | EP | disclosed |
| US-6388086-B1 | REACTING W 3-METHYLPYRIDINE WITH BASE; THEN EPOXY COMPOUND | KANEKA CORPORATION (JP) | 2002-05-14 | — | — | US | disclosed |
| EP-1074544-A1 | Process for production of 3-(3-pyridyl)-1-propanol derivatives | KANEKA CORPORATION (JP) | 2001-02-07 | — | — | EP | disclosed |