SCHEMBL695145

SCHEMBL695145

OCc1ccc(OCc2ccccc2)cc1C(F)(F)F

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
AR P10275 1/20 0.52
ALOX5 P09917 1/20 0.50
MAOB P27338 6/20 0.49
PDK2 Q15119 1/20 0.49
CYP4F2 P78329 1/20 0.49
CYP4A11 Q02928 1/20 0.49
LMNA P02545 1/20 0.49
CYP1A2 P05177 1/20 0.49
PTGS1 P23219 1/20 0.49
SLC6A2 P23975 1/20 0.49
CYP2C19 P33261 1/20 0.49
PTGS2 P35354 1/20 0.49
SLC6A3 Q01959 1/20 0.49
HIF1A Q16665 1/20 0.49
HDAC6 Q9UBN7 1/20 0.49
MRGPRX4 Q96LA9 1/20 0.46
GSTP1 P09211 1/20 0.45
LTA4H P09960 1/20 0.45
EPHX2 P34913 1/20 0.45
NR4A2 P43354 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL694270 0.87 AR (0.51) ARALOX5MAOBPDK2LMNA
SCHEMBL27347638 0.83 MEN1 (0.47) ARALOX5PDK2CYP4F2CYP4A11
SCHEMBL8761070 0.82 ALOX5 (0.58) ALOX5MAOBCYP4F2CYP4A11LMNA
SCHEMBL5540079 0.82 AR (0.50) ARALOX5MAOBPDK2MRGPRX4
SCHEMBL5540071 0.82 AR (0.50) ARALOX5MAOBPDK2MRGPRX4
SCHEMBL3770492 0.81 MAOB (0.55) ALOX5MAOBCYP4F2CYP4A11LMNA
SCHEMBL629746 0.81 MAOB (0.66) ALOX5MAOBCYP4F2CYP4A11LMNA
SCHEMBL1941274 0.81 MAOB (0.57) ARMAOBMRGPRX4NR4A2
SCHEMBL5017371 0.80 AR (0.53) ARALOX5MAOBPDK2LMNA
SCHEMBL8808194 0.80 AR (0.53) ARALOX5MAOBPDK2LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 58 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3526300-A1 CONTACT ADHESIVES Clariant Plastics & Coatings Ltd (CH) 2019-08-21 EP disclosed
WO-2018073088-A1 CONTACT ADHESIVES CLARIANT PLASTICS & COATINGS LTD (CH) 2018-04-26 WO disclosed
EP-3289027-A1 SHORT-CHAIN POLYETHYLENE HOMOPOLYMERS HAVING IMPROVED GRINDABILITY Clariant International Ltd (CH) 2018-03-07 EP disclosed
EP-2976403-B1 READY-TO-USE HOT MELT ADHESIVE HAVING AN IMPROVED PROPERTY PROFILE CLARIANT INT LTD (CH) 2017-08-16 EP disclosed
WO-2016174019-A1 SHORT-CHAIN POLYETHYLENE HOMOPOLYMERS HAVING IMPROVED GRINDABILITY CLARIANT INTERNATIONAL LTD (CH) 2016-11-03 WO disclosed
EP-2079779-B1 ACTIVE SUBSTANCE COMPOSITION ON THE BASIS OF METALLOCENE POLYOLEFIN WAXES FOR PRODUCING STABILIZED, LIGHT-RESISTANT PLASTIC MATERIALS CLARIANT INT LTD (CH) 2016-04-20 EP disclosed
EP-2976403-A1 READY-TO-USE HOT MELT ADHESIVE HAVING AN IMPROVED PROPERTY PROFILE Clariant International Ltd. (CH) 2016-01-27 EP disclosed
EP-2081980-B1 TEMPERATURE-SENSITIVE ACTIVE INGREDIENT COMPOSITIONS FOR REDUCING THE DENSITY OF PLASTICS CLARIANT FINANCE BVI LTD (VG) 2015-02-25 EP disclosed
WO-2014154328-A1 READY-TO-USE HOT MELT ADHESIVE HAVING AN IMPROVED PROPERTY PROFILE CLARIANT INTERNATIONAL LTD (CH) 2014-10-02 WO disclosed
US-8399436-B2 N-pyrazolyl carboxamides as CRAC channel inhibitors GLAXO GROUP LIMITED (GB) 2013-03-19 US disclosed
EP-1645608-A1 Use of polyolefin waxes in hot melts Clariant Produkte (Deutschland) GmbH (DE) 2006-04-12 EP disclosed
EP-1631641-A1 HOT-MELT ADHESIVE MATERIALS Clariant GmbH (DE) 2006-03-08 EP disclosed
EP-1619010-A1 Use of polyolefin waxes in polycondensates Clariant GmbH (DE) 2006-01-25 EP disclosed
EP-1605013-A1 Expandable polystyrene Clariant GmbH (DE) 2005-12-14 EP disclosed
EP-1508579-A1 Modified polyolefin waxes Clariant GmbH (DE) 2005-02-23 EP disclosed
WO-2004104128-A1 HOT-MELT ADHESIVE MATERIALS CLARIANT GMBH (DE) 2004-12-02 WO disclosed
EP-0890619-B1 Use of polyolefinwaxes CLARIANT GMBH (DE) 2004-10-27 EP disclosed
EP-0890583-B1 Process for the oxidation of polyethylene waxes CLARIANT GMBH (DE) 2003-10-29 EP disclosed
EP-0890619-A1 Use of polyolefinwaxes Clariant GmbH (DE) 1999-01-13 EP disclosed
EP-0890583-A1 Process for the oxidation of polyethylene waxes Clariant GmbH (DE) 1999-01-13 EP disclosed