Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.34 |
| ▸ | CACNA1G | O43497 | 2/20 | 0.34 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.33 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.33 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.32 |
| ▸ | F10 | P00742 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | MMP2 | P08253 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | BRS3 | P32247 | 1/20 | 0.31 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.31 |
| ▸ | TUBB | P07437 | 1/20 | 0.31 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.31 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.31 |
| ▸ | TUBA4A | P68366 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6947176 | 0.83 | MAPT (0.38) | MAPTHSD17B10HDAC6HDAC1NTRK1 | |
| SCHEMBL6945352 | 0.80 | HDAC6 (0.39) | MAPTHDAC6HDAC1NTRK1ALDH1A1 | |
| SCHEMBL6952475 | 0.79 | HDAC1 (0.36) | MAPTHDAC6HDAC1ALDH1A1NPC1 | |
| SCHEMBL6954314 | 0.77 | MAPT (0.43) | MAPTHSD17B10HDAC6HDAC1NTRK1 | |
| Hydrochloric Acid SCHEMBL6949937 | 0.76 | MAPT (0.42) | MAPTHSD17B10HDAC6HDAC1F10 | |
| SCHEMBL6945281 | 0.74 | MAPT (0.47) | MAPTHSD17B10CACNA1GHDAC6HDAC1 | |
| SCHEMBL6946457 | 0.74 | MAPT (0.41) | MAPTHSD17B10HDAC6HDAC1NTRK1 | |
| SCHEMBL6950396 | 0.69 | MAPT (0.48) | MAPTHSD17B10CACNA1GHDAC6NTRK1 | |
| Hydrochloric Acid SCHEMBL6953896 | 0.68 | MAPT (0.47) | MAPTHSD17B10HDAC6NTRK1F10 | |
| SCHEMBL6954309 | 0.68 | MAPT (0.43) | MAPTHSD17B10HDAC6HDAC1NTRK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0936218-B1 | BENZIMIDAZOLE DERIVATIVES | MOCHIDA PHARM CO LTD (JP) | 2003-04-02 | — | — | EP | disclosed |
| US-6387938-B1 | Benzimidazole derivatives | MOCHIDA PHARMACEUTICAL CO., LTD. (JP) | 2002-05-14 | — | — | US | disclosed |
| EP-0936218-A1 | NOVEL BENZIMIDAZOLE DERIVATIVES | MOCHIDA PHARMACEUTICAL CO., LTD. (JP) | 1999-08-18 | — | — | EP | disclosed |