Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 2/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | ADORA2B | P29275 | 4/20 | 0.31 |
| ▸ | ADORA2A | P29274 | 2/20 | 0.31 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.30 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.30 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1984602 | 0.80 | MAPK1 (0.40) | MAPK1CYP3A4POLBHTTADORA2B | |
| SCHEMBL7248981 | 0.72 | MAPT (0.35) | MAPK1POLBHTTADORA2BADORA2A | |
| SCHEMBL5397038 | 0.72 | POLB (0.37) | MAPK1CYP3A4POLBHTTADORA2B | |
| SCHEMBL11245537 | 0.71 | CYP3A4 (0.46) | CYP3A4POLBADORA2BADORA2AADORA3 | |
| SCHEMBL5657557 | 0.70 | POLB (0.33) | MAPK1POLBHTTADORA2BADORA3 | |
| SCHEMBL5656943 | 0.70 | POLB (0.36) | MAPK1POLBHTTADORA2BADORA2A | |
| SCHEMBL6950271 | 0.64 | CYP11B1 (0.44) | MAPK1ADORA2B | |
| SCHEMBL5654666 | 0.64 | MLYCD (0.33) | POLB | |
| SCHEMBL7252343 | 0.64 | MAPK1 (0.40) | MAPK1POLBHTT | |
| SCHEMBL7806190 | 0.63 | CYP3A4 (0.38) | CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6630593-B1 | A process for preparing a 1-substituted 5-hydroxymethylimidazole of the formula: wherein R represents alkyl, hydroxyalkyl, allyl, or substituted or unsubstituted arylmethyl or diarylmethyl, comprising the step of reacting a | LG CHEM INVESTMENT LTD. (KR) | 2003-10-07 | — | — | US | disclosed |
| EP-1255737-A4 | PROCESS FOR PREPARING A 1-SUBSTITUTED 5-HYDROXYMETHYL IMIDAZOLE | LG CHEM INVESTMENT LTD (KR) | 2003-04-16 | — | — | EP | disclosed |
| EP-1255737-A1 | PROCESS FOR PREPARING A 1-SUBSTITUTED 5-HYDROXYMETHYL IMIDAZOLE | LG Chem Investment, Ltd. (KR) | 2002-11-13 | — | — | EP | disclosed |
| WO-2001017974-A1 | PROCESS FOR PREPARING A 1-SUBSTITUTED 5-HYDROXYMETHYL IMIDAZOLE | LG CHEM INVESTMENT LTD. (KR) | 2001-03-15 | — | — | WO | disclosed |