Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR4 | Q13639 | 12/20 | 0.45 |
| ▸ | CACNA1I | Q9P0X4 | 3/20 | 0.43 |
| ▸ | KCNH2 | Q12809 | 3/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6327508 | 0.96 | HTR4 (0.47) | HTR4CACNA1IKCNH2 | |
| SCHEMBL6335673 | 0.87 | HTR4 (0.49) | HTR4CACNA1IKCNH2 | |
| SCHEMBL14258189 | 0.85 | NR4A2 (0.53) | HTR4 | |
| SCHEMBL6331443 | 0.85 | HTR4 (0.48) | HTR4CACNA1IKCNH2 | |
| SCHEMBL6329736 | 0.84 | KCNH2 (0.49) | HTR4CACNA1IKCNH2 | |
| Hydrochloric Acid SCHEMBL6326593 | 0.84 | NR4A2 (0.52) | HTR4 | |
| SCHEMBL6329265 | 0.84 | HTR4 (0.46) | HTR4CACNA1IKCNH2 | |
| SCHEMBL6328884 | 0.84 | CACNA1I (0.53) | HTR4CACNA1IKCNH2 | |
| SCHEMBL6331058 | 0.84 | GSK3B (0.47) | HTR4CACNA1IKCNH2 | |
| N-Propyl Bromide SCHEMBL7255030 | 0.83 | HTR4 (0.46) | HTR4CACNA1IKCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1325921-A2 | Oxo or oxy-pyridine compounds as 5-HT4 receptor modulators | Pfizer Inc. (US) | 2003-07-09 | — | — | EP | disclosed |