Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EED | O75530 | 1/20 | 0.31 |
| ▸ | RBBP4 | Q09028 | 1/20 | 0.31 |
| ▸ | SUZ12 | Q15022 | 1/20 | 0.31 |
| ▸ | AEBP2 | Q6ZN18 | 1/20 | 0.31 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6952198 | 1.00 | EED (0.31) | EEDRBBP4SUZ12AEBP2CYP2A6 | |
| SCHEMBL6949125 | 0.81 | CYP2A6 (0.31) | CYP2A6 | |
| SCHEMBL6949118 | 0.81 | CYP2A6 (0.31) | CYP2A6 | |
| SCHEMBL6957213 | 0.74 | CYP2A6 (0.39) | CYP2A6 | |
| SCHEMBL6948659 | 0.71 | — | — | |
| SCHEMBL6948653 | 0.71 | — | — | |
| SCHEMBL29473759 | 0.70 | CYP2A6 (0.39) | EEDRBBP4SUZ12AEBP2CYP2A6 | |
| SCHEMBL17841499 | 0.70 | CYP2A6 (0.39) | EEDRBBP4SUZ12AEBP2CYP2A6 | |
| SCHEMBL2585106 | 0.67 | MAOA (0.38) | — | |
| SCHEMBL24036411 | 0.64 | MAOA (0.36) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0901483-B1 | BENZOFURANS AND BENZOPYRANS AS CHRONOBIOLOGICAL AGENTS | GLAXO GROUP LTD (GB) | 2003-07-09 | — | — | EP | disclosed |
| US-5981572-A | Benzofurans and benzopyrans as chronobiological agents | GLAXO WELLCOME INC. (US) | 1999-11-09 | — | — | US | disclosed |