Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | REN | P00797 | 14/20 | 0.39 |
| ▸ | RXRB | P28702 | 1/20 | 0.35 |
| ▸ | TACR1 | P25103 | 1/20 | 0.33 |
| ▸ | MC4R | P32245 | 1/20 | 0.33 |
| ▸ | KLK7 | P49862 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.32 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7081059 | 0.91 | REN (0.44) | REN | |
| SCHEMBL6952320 | 0.87 | REN (0.37) | REN | |
| SCHEMBL7081006 | 0.86 | REN (0.52) | REN | |
| SCHEMBL6043716 | 0.86 | REN (0.42) | RENRXRBTSHRMAPK1 | |
| SCHEMBL27488568 | 0.85 | REN (0.46) | REN | |
| SCHEMBL6957251 | 0.83 | MEN1 (0.34) | — | |
| SCHEMBL7078346 | 0.81 | REN (0.34) | REN | |
| SCHEMBL6951729 | 0.81 | REN (0.46) | REN | |
| SCHEMBL6957468 | 0.80 | MC4R (0.37) | RENRXRBTACR1MC4R | |
| SCHEMBL7075237 | 0.79 | REN (0.56) | REN |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0863875-B1 | NEW 4-(OXYALKOXYPHENYL)-3-OXY-PIPERIDINES FOR TREATING HEART AND KIDNEY INSUFFICIENCY | HOFFMANN LA ROCHE (CH) | 2003-06-04 | — | — | EP | disclosed |