Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.55 |
| ▸ | TSHR | P16473 | 2/20 | 0.55 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.50 |
| ▸ | ATG4B | Q9Y4P1 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | NPC1 | O15118 | 2/20 | 0.46 |
| ▸ | RAB9A | P51151 | 2/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | ADRB2 | P07550 | 8/20 | 0.44 |
| ▸ | ADRB1 | P08588 | 8/20 | 0.44 |
| ▸ | ADRB3 | P13945 | 8/20 | 0.44 |
| ▸ | JMJD6 | Q6NYC1 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL110051 | 0.86 | ALDH1A1 (0.64) | ALDH1A1TSHRPLA2G1BATG4BMAPT | |
| SCHEMBL9724768 | 0.84 | MAPT (0.69) | ALDH1A1TSHRMAPTRAB9AADRB2 | |
| SCHEMBL9724765 | 0.84 | MAPT (0.69) | ALDH1A1TSHRMAPTRAB9AADRB2 | |
| SCHEMBL27667934 | 0.84 | ALDH1A1 (0.62) | ALDH1A1TSHRPLA2G1BATG4BMAPT | |
| SCHEMBL27668055 | 0.84 | ALDH1A1 (0.62) | ALDH1A1TSHRPLA2G1BATG4BMAPT | |
| SCHEMBL27668352 | 0.84 | ALDH1A1 (0.62) | ALDH1A1TSHRPLA2G1BATG4BMAPT | |
| SCHEMBL9787311 | 0.82 | MAPK1 (0.59) | ALDH1A1TSHRMAPT | |
| Benzoic Acid 2-Methylpropyl Ester SCHEMBL20530394 | 0.81 | TSHR (0.69) | ALDH1A1TSHRPLA2G1BATG4BMAPT | |
| Benzoic Acid 2-Methylpropyl Ester SCHEMBL298176 | 0.81 | TSHR (0.69) | ALDH1A1TSHRPLA2G1BATG4BMAPT | |
| SCHEMBL8809828 | 0.80 | TSHR (0.49) | ALDH1A1TSHRPLA2G1BATG4BMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0936218-B1 | BENZIMIDAZOLE DERIVATIVES | MOCHIDA PHARM CO LTD (JP) | 2003-04-02 | — | — | EP | disclosed |
| US-6387938-B1 | Benzimidazole derivatives | MOCHIDA PHARMACEUTICAL CO., LTD. (JP) | 2002-05-14 | — | — | US | disclosed |
| US-6020426-A | BLOCK OR GRAFT COPOLYMER | FUJI XEROX CO., LTD. (JP) | 2000-02-01 | — | — | US | disclosed |
| EP-0936218-A1 | NOVEL BENZIMIDAZOLE DERIVATIVES | MOCHIDA PHARMACEUTICAL CO., LTD. (JP) | 1999-08-18 | — | — | EP | disclosed |
| US-5670563-A | ORGANOTIN COMPOUND, PHOSPHORUS COMPOUND | CIBA-SPECIALTY CHEMICALS CORPORATION (US) | 1997-09-23 | — | — | US | disclosed |
| US-4988662-A | MULTILAYER ELEMENT OF A COATED SUBSTRATE, A FILM WITH A COLOR-FORMING LACTONE, AN ACID AND A SENSITIZER | DAINIPPON INK AND CHEMICALS, INC. (JP) | 1991-01-29 | — | — | US | disclosed |