Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP2 | P08253 | 1/20 | 0.44 |
| ▸ | PLA2G2A | P14555 | 3/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | BLM | P54132 | 1/20 | 0.41 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.41 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | NTRK1 | P04629 | 3/20 | 0.41 |
| ▸ | PDE4A | P27815 | 1/20 | 0.41 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.41 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL6953964 | 0.93 | MMP2 (0.45) | MMP2PLA2G2AMAPTALDH1A1NTRK1 | |
| SCHEMBL6951919 | 0.85 | NPC1 (0.43) | NTRK1PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL6949171 | 0.85 | NPC1 (0.45) | NTRK1PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL6953197 | 0.84 | MMP2 (0.44) | MMP2PLA2G2AMAPTALDH1A1CYP1A2 | |
| SCHEMBL6949863 | 0.84 | SCN1A (0.42) | MAPTALDH1A1CYP1A2CYP2D6CYP2C9 | |
| SCHEMBL6953656 | 0.78 | MAPT (0.44) | MAPTALDH1A1CYP1A2CYP3A4CYP2D6 | |
| Hydrochloric Acid SCHEMBL6953955 | 0.77 | MMP2 (0.45) | MMP2PLA2G2AMAPTALDH1A1CYP1A2 | |
| SCHEMBL10360805 | 0.76 | KDM4E (0.52) | MAPTALDH1A1CYP1A2CYP3A4CYP2D6 | |
| SCHEMBL6946613 | 0.76 | MMP2 (0.50) | MMP2PLA2G2AMAPTALDH1A1NTRK1 | |
| SCHEMBL6948946 | 0.76 | NPC1 (0.46) | MMP2MAPTALDH1A1NTRK1PDE4A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0936218-B1 | BENZIMIDAZOLE DERIVATIVES | MOCHIDA PHARM CO LTD (JP) | 2003-04-02 | — | — | EP | disclosed |
| US-6387938-B1 | Benzimidazole derivatives | MOCHIDA PHARMACEUTICAL CO., LTD. (JP) | 2002-05-14 | — | — | US | disclosed |
| EP-0936218-A1 | NOVEL BENZIMIDAZOLE DERIVATIVES | MOCHIDA PHARMACEUTICAL CO., LTD. (JP) | 1999-08-18 | — | — | EP | disclosed |