Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.52 |
| ▸ | GAA | P10253 | 2/20 | 0.52 |
| ▸ | MAPT | P10636 | 2/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.52 |
| ▸ | PHGDH | O43175 | 3/20 | 0.51 |
| ▸ | MEN1 | O00255 | 5/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.50 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.50 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.50 |
| ▸ | PKM | P14618 | 1/20 | 0.50 |
| ▸ | POLB | P06746 | 3/20 | 0.49 |
| ▸ | NPC1 | O15118 | 1/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27556985 | 0.91 | MEN1 (0.63) | LMNAGAAMAPTALDH1A1PHGDH | |
| SCHEMBL6652129 | 0.89 | PHGDH (0.50) | LMNAGAAMAPTALDH1A1PHGDH | |
| SCHEMBL8699629 | 0.89 | KDM4E (0.57) | LMNAGAAMAPTALDH1A1SMN1; SMN2 | |
| SCHEMBL9057398 | 0.88 | GAA (0.51) | LMNAGAAMAPTALDH1A1SMN1; SMN2 | |
| SCHEMBL6953108 | 0.88 | GAA (0.51) | LMNAGAAMAPTALDH1A1SMN1; SMN2 | |
| SCHEMBL7084407 | 0.88 | MAPT (0.53) | LMNAGAAMAPTALDH1A1SMN1; SMN2 | |
| SCHEMBL6654161 | 0.85 | PHGDH (0.60) | LMNAALDH1A1PHGDHMEN1KMT2A | |
| SCHEMBL6651537 | 0.85 | CYP3A4 (0.61) | LMNAALDH1A1PHGDHMEN1KMT2A | |
| SCHEMBL6657881 | 0.84 | PHGDH (0.56) | LMNAALDH1A1PHGDHMEN1KMT2A | |
| SCHEMBL27541031 | 0.84 | CYP3A4 (0.52) | LMNAALDH1A1PHGDHMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1152015-C | Piperazine devivatives and process for preparation thereof | ������ҩ��ʽ���� | 2004-06-02 | — | — | CN | disclosed |
| EP-0850222-B1 | PIPERAZINE DERIVATIVES AND PROCESS FOR THE PREPARATION THEREOF | SAMJIN PHARM CO LTD (KR) | 2003-05-28 | — | — | EP | disclosed |
| US-6028195-A | AN ANTITUMOR AGENT WITH VERY LOW TOXICITIES | SAMJIN PHARMACEUTICAL CO., LTD. (KR) | 2000-02-22 | — | — | US | disclosed |