Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.57 |
| ▸ | LMNA | P02545 | 4/20 | 0.53 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.53 |
| ▸ | MAPT | P10636 | 7/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.51 |
| ▸ | HTT | P42858 | 4/20 | 0.51 |
| ▸ | PHGDH | O43175 | 1/20 | 0.50 |
| ▸ | GAA | P10253 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 8/20 | 0.49 |
| ▸ | MEN1 | O00255 | 7/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.49 |
| ▸ | HPGD | P15428 | 1/20 | 0.49 |
| ▸ | PKM | P14618 | 1/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.49 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.49 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.48 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.48 |
| ▸ | POLB | P06746 | 3/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27556985 | 0.90 | MEN1 (0.63) | LMNAMAPTALDH1A1PHGDHGAA | |
| SCHEMBL6652246 | 0.90 | PHGDH (0.55) | KDM4EMAPTALDH1A1PHGDHGAA | |
| SCHEMBL8699119 | 0.89 | KDM4E (0.55) | KDM4ELMNARXFP1MAPTALDH1A1 | |
| SCHEMBL6953207 | 0.89 | LMNA (0.52) | KDM4ELMNAMAPTALDH1A1PHGDH | |
| SCHEMBL8700254 | 0.89 | GAA (0.56) | KDM4ELMNAMAPTALDH1A1HTT | |
| SCHEMBL6652129 | 0.88 | PHGDH (0.50) | KDM4ELMNAMAPTALDH1A1PHGDH | |
| SCHEMBL6650903 | 0.85 | KDM4E (0.59) | KDM4ELMNARXFP1MAPTALDH1A1 | |
| SCHEMBL6651537 | 0.84 | CYP3A4 (0.61) | LMNAALDH1A1PHGDHKMT2AMEN1 | |
| SCHEMBL6654161 | 0.84 | PHGDH (0.60) | LMNAALDH1A1HTTPHGDHKMT2A | |
| SCHEMBL6780980 | 0.83 | KDM4E (0.61) | KDM4ELMNARXFP1MAPTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5780472-A | ANTITUMOR AGENTS | SAMJIN PHARMACEUTICAZL CO., LTD. (KR) | 1998-07-14 | — | — | US | disclosed |
| WO-1996021648-A1 | NEW PIPERAZINE DERIVATIVES AND METHODS FOR THE PREPARATION THEREOF AND COMPOSITIONS CONTAINING THE SAME | SAMJIN PHARMACEUTICAL CO., LTD. (KR) | 1996-07-18 | — | — | WO | disclosed |