Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.72 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.62 |
| ▸ | GRIN1 | Q05586 | 4/20 | 0.50 |
| ▸ | GRIN2B | Q13224 | 4/20 | 0.50 |
| ▸ | GRIN2D | O15399 | 3/20 | 0.50 |
| ▸ | GRIN3B | O60391 | 3/20 | 0.50 |
| ▸ | GRIN2A | Q12879 | 3/20 | 0.50 |
| ▸ | GRIN2C | Q14957 | 3/20 | 0.50 |
| ▸ | GRIN3A | Q8TCU5 | 3/20 | 0.50 |
| ▸ | FURIN | P09958 | 2/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
| ▸ | BCHE | P06276 | 1/20 | 0.50 |
| ▸ | EGFR | P00533 | 1/20 | 0.49 |
| ▸ | G6PC1 | P35575 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | MAOB | P27338 | 1/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6953455 | 1.00 | TAAR1 (0.72) | TAAR1CHRM5GRIN1GRIN2BGRIN2D | |
| SCHEMBL6953452 | 1.00 | TAAR1 (0.72) | TAAR1CHRM5GRIN1GRIN2BGRIN2D | |
| SCHEMBL7719407 | 0.81 | NPC1 (0.59) | TAAR1GRIN1GRIN2BGRIN2DGRIN3B | |
| SCHEMBL7719409 | 0.81 | NPC1 (0.59) | TAAR1GRIN1GRIN2BGRIN2DGRIN3B | |
| SCHEMBL7719406 | 0.81 | NPC1 (0.59) | TAAR1GRIN1GRIN2BGRIN2DGRIN3B | |
| SCHEMBL15583383 | 0.80 | GRIN2D (0.68) | TAAR1GRIN1GRIN2BGRIN2DGRIN3B | |
| SCHEMBL29607358 | 0.79 | TAAR1 (0.74) | TAAR1CHRM5GRIN1GRIN2BGRIN2D | |
| SCHEMBL1654602 | 0.78 | CHRM5 (1.00) | TAAR1CHRM5G6PC1NPC1 | |
| SCHEMBL10689025 | 0.75 | MEN1 (0.64) | TAAR1CHRM5MEN1ALDH1A1KMT2A | |
| SCHEMBL10689034 | 0.75 | MEN1 (0.64) | TAAR1CHRM5MEN1ALDH1A1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1103549-B1 | Photoprotective cosmetic compositions containing aminoamidine derivatives and uses thereof | OREAL (FR) | 2003-06-04 | — | — | EP | claimed |
| US-6379655-B1 | FOR PROTECTION OF HUMAN SKIN AND/OR HAIR AGAINST THE DAMAGING EFFECTS OF ULTRAVIOLET IRRADIATION | SOCIETE L'OREAL S.A. (FR) | 2002-04-30 | — | — | US | claimed |
| EP-1103549-A1 | Photoprotective cosmetic compositions containing aminoamidine derivatives and uses thereof | L'OREAL (FR) | 2001-05-30 | — | — | EP | claimed |
| EP-1103549-B1 | Photoprotective cosmetic compositions containing aminoamidine derivatives and uses thereof | OREAL (FR) | 2003-06-04 | — | — | EP | disclosed |
| US-6379655-B1 | FOR PROTECTION OF HUMAN SKIN AND/OR HAIR AGAINST THE DAMAGING EFFECTS OF ULTRAVIOLET IRRADIATION | SOCIETE L'OREAL S.A. (FR) | 2002-04-30 | — | — | US | disclosed |
| EP-1103549-A1 | Photoprotective cosmetic compositions containing aminoamidine derivatives and uses thereof | L'OREAL (FR) | 2001-05-30 | — | — | EP | disclosed |