Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 1/20 | 0.59 |
| ▸ | CASP3 | P42574 | 1/20 | 0.59 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.59 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.59 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.59 |
| ▸ | FURIN | P09958 | 1/20 | 0.51 |
| ▸ | GRIN2D | O15399 | 7/20 | 0.49 |
| ▸ | GRIN3B | O60391 | 7/20 | 0.49 |
| ▸ | GRIN1 | Q05586 | 7/20 | 0.49 |
| ▸ | GRIN2A | Q12879 | 7/20 | 0.49 |
| ▸ | GRIN2B | Q13224 | 7/20 | 0.49 |
| ▸ | GRIN2C | Q14957 | 7/20 | 0.49 |
| ▸ | GRIN3A | Q8TCU5 | 7/20 | 0.49 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.49 |
| ▸ | RAB9A | P51151 | 2/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | HPGD | P15428 | 1/20 | 0.48 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7719407 | 1.00 | NPC1 (0.59) | NPC1CASP3SENP8SENP7SENP6 | |
| SCHEMBL7719406 | 1.00 | NPC1 (0.59) | NPC1CASP3SENP8SENP7SENP6 | |
| SCHEMBL15583383 | 0.84 | GRIN2D (0.68) | NPC1FURINGRIN2DGRIN3BGRIN1 | |
| SCHEMBL6953455 | 0.81 | TAAR1 (0.72) | NPC1FURINGRIN2DGRIN3BGRIN1 | |
| SCHEMBL6953458 | 0.81 | TAAR1 (0.72) | NPC1FURINGRIN2DGRIN3BGRIN1 | |
| SCHEMBL6953452 | 0.81 | TAAR1 (0.72) | NPC1FURINGRIN2DGRIN3BGRIN1 | |
| Hydrochloric Acid SCHEMBL5703078 | 0.81 | FURIN (0.73) | NPC1CASP3SENP8SENP7SENP6 | |
| SCHEMBL22044441 | 0.79 | PARP1 (0.55) | NPC1RAB9AHPGDSMN1; SMN2 | |
| SCHEMBL14610953 | 0.77 | NPC1 (0.66) | NPC1CASP3SENP8SENP7SENP6 | |
| SCHEMBL11749167 | 0.76 | NPC1 (1.00) | NPC1CASP3SENP8SENP7SENP6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6379655-B1 | FOR PROTECTION OF HUMAN SKIN AND/OR HAIR AGAINST THE DAMAGING EFFECTS OF ULTRAVIOLET IRRADIATION | SOCIETE L'OREAL S.A. (FR) | 2002-04-30 | — | — | US | claimed |
| US-6379655-B1 | FOR PROTECTION OF HUMAN SKIN AND/OR HAIR AGAINST THE DAMAGING EFFECTS OF ULTRAVIOLET IRRADIATION | SOCIETE L'OREAL S.A. (FR) | 2002-04-30 | — | — | US | disclosed |