Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 4/20 | 0.61 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.61 |
| ▸ | MEN1 | O00255 | 3/20 | 0.61 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.61 |
| ▸ | GAA | P10253 | 2/20 | 0.61 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.61 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.61 |
| ▸ | HPGD | P15428 | 1/20 | 0.61 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.59 |
| ▸ | LMNA | P02545 | 3/20 | 0.59 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.59 |
| ▸ | RAB9A | P51151 | 3/20 | 0.52 |
| ▸ | POLB | P06746 | 3/20 | 0.51 |
| ▸ | NPC1 | O15118 | 2/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | THRB | P10828 | 1/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.45 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.45 |
| ▸ | TP53 | P04637 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6957506 | 0.92 | MAPK1 (0.58) | HTTSMN1; SMN2MEN1KMT2AGAA | |
| SCHEMBL6948903 | 0.91 | MAPK1 (0.57) | HTTSMN1; SMN2MEN1KMT2AGAA | |
| SCHEMBL6952202 | 0.84 | PPARG (0.45) | HTTSMN1; SMN2MEN1KMT2AGAA | |
| SCHEMBL6956510 | 0.82 | HDAC6 (0.52) | HTTSMN1; SMN2GAACYP2C9CYP2C19 | |
| SCHEMBL6555749 | 0.82 | PPARG (0.64) | HTTSMN1; SMN2MEN1KMT2AGAA | |
| SCHEMBL6957110 | 0.81 | MAPK1 (0.62) | HTTSMN1; SMN2MEN1KMT2AGAA | |
| SCHEMBL6955465 | 0.79 | MAPK1 (0.59) | HTTSMN1; SMN2MEN1KMT2AGAA | |
| SCHEMBL6956607 | 0.79 | HTT (0.63) | HTTSMN1; SMN2MEN1KMT2AGAA | |
| SCHEMBL6955730 | 0.79 | NPC1 (0.62) | SMN1; SMN2KMT2AALDH1A1RAB9APOLB | |
| SCHEMBL6957510 | 0.78 | MAPK1 (0.57) | HTTSMN1; SMN2MEN1KMT2AGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0903343-B1 | Alpha-Substituted phenylpropionic acid derivative and medicine containing the same | SSP CO LTD (JP) | 2003-05-28 | — | — | EP | disclosed |
| EP-0903343-A1 | Alpha-Substituted phenylpropionic acid derivative and medicine containing the same | SSP Co., Ltd. (JP) | 1999-03-24 | — | — | EP | disclosed |