Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 14/20 | 0.45 |
| ▸ | PPARA | Q07869 | 11/20 | 0.45 |
| ▸ | PPARD | Q03181 | 5/20 | 0.45 |
| ▸ | TNF | P01375 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | PSMB1 | P20618 | 1/20 | 0.40 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6954580 | 0.91 | TNF (0.41) | PPARGPPARAPPARDTNFHTT | |
| SCHEMBL6957154 | 0.90 | TNF (0.49) | PPARGPPARAPPARDTNFHTT | |
| SCHEMBL6953552 | 0.84 | HTT (0.61) | HTTMEN1ALDH1A1GAACYP2C9 | |
| SCHEMBL6955730 | 0.83 | NPC1 (0.62) | PPARGPPARAPPARDALDH1A1KMT2A | |
| SCHEMBL6957273 | 0.81 | PPARG (0.47) | PPARGPPARAPPARDTNFRAB9A | |
| SCHEMBL6956263 | 0.79 | PPARG (0.45) | PPARGPPARAPPARDTNFPSMB1 | |
| SCHEMBL6949013 | 0.78 | PPARG (0.47) | PPARGPPARAPPARD | |
| SCHEMBL6954585 | 0.78 | TNF (0.41) | PPARGPPARAPPARDTNFHTT | |
| SCHEMBL6956510 | 0.77 | HDAC6 (0.52) | PPARGHTTGAACYP2C9HPGD | |
| SCHEMBL6948727 | 0.76 | PPARG (0.56) | PPARGPPARAPPARDTNFRAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0903343-B1 | Alpha-Substituted phenylpropionic acid derivative and medicine containing the same | SSP CO LTD (JP) | 2003-05-28 | — | — | EP | disclosed |
| EP-0903343-A1 | Alpha-Substituted phenylpropionic acid derivative and medicine containing the same | SSP Co., Ltd. (JP) | 1999-03-24 | — | — | EP | disclosed |