⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19783669 | 0.88 | TSHR (0.41) | — | |
| SCHEMBL2745371 | 0.80 | — | — | |
| SCHEMBL8444152 | 0.79 | — | — | |
| SCHEMBL10437706 | 0.75 | — | — | |
| SCHEMBL10577984 | 0.73 | — | — | |
| SCHEMBL896440 | 0.73 | — | — | |
| SCHEMBL28902729 | 0.73 | LMNA (0.47) | — | |
| SCHEMBL421767 | 0.71 | — | — | |
| SCHEMBL14833168 | 0.71 | — | — | |
| SCHEMBL10575997 | 0.71 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105442083-B | A kind of preparation method of reactive dye easy dyeing spandex | 浙江华峰氨纶股份有限公司 | 2017-09-12 | — | — | CN | disclosed |
| CN-105442083-A | Preparation method of spandex with reactive dye easy-dying function | ZHEJIANG HUAFENG SPANDEX CO LTD | 2016-03-30 | — | — | CN | disclosed |
| WO-2013001498-A1 | AMIDOALKYLPIPERAZINYL DERIVATIVES FOR THE TREATMENT OF CENTRAL NERVOUS SYSTEM DISEASES | ADAMED SP. Z O.O. (PL) | 2013-01-03 | — | — | WO | disclosed |
| EP-0991644-B1 | BENZO(5,6)CYCLOHEPTAPYRIDINE CYCLIC UREAS AND LACTAMS USEFUL AS FARNESYL PROTEIN TRANSFERASE INHIBITORS | SCHERING CORP (US) | 2003-04-16 | — | — | EP | disclosed |
| EP-0991644-A1 | BENZO(5,6)CYCLOHEPTAPYRIDINE CYCLIC UREAS AND LACTAMS USEFUL AS FARNESYL PROTEIN TRANSFERASE INHIBITORS | SCHERING CORPORATION (US) | 2000-04-12 | — | — | EP | disclosed |
| US-6039683-A | Benzo(5,6)cycloheptapyridine cyclic ureas and lactams useful as farnesyl protein transferase inhibitors | SCHERING CORPORATION (US) | 2000-03-21 | — | — | US | disclosed |
| WO-1998057963-A1 | BENZO(5,6)CYCLOHEPTAPYRIDINE CYCLIC UREAS AND LACTAMS USEFUL AS FARNESYL PROTEIN TRANSFERASE INHIBITORS | SCHERING CORPORATION (US) | 1998-12-23 | — | — | WO | disclosed |
| US-5852034-A | Benzo(5,6)cycloheptapyridine cyclic ureas and lactams useful as farnesyl protein transferase inhibitors | SCHERING CORPORATION (US) | 1998-12-22 | — | — | US | disclosed |